ArticleJournal of medical biochemistry2018
Evaluation of Biochemical Hyperandrogenism in Adolescent Girls with Menstrual Irregularities.
Article in Journal of medical biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 4 citations in OpenAlex.
- Presence of hyperandrogenemia in cases evaluated due to menstrual irregularity, the effect of clinical and/or biochemical hyperandrogenemia on polycystic ovary syndrome.Journal of pediatric endocrinology & metabolism : JPEM · 2025Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to evaluate fertility hormone levels in adolescent girls and ten years older women with menstrual irregularities and with or without polycystic ovaries on ultrasound examination. The study population consisted of 276 patients aged 12-18 years and 469 patients aged 22-28 years who had menstrual irregularities with or without polycystic ovaries on ultrasound examination.
methodsAll subjects underwent a comprehensive medical assessment including documentation of the detailed history, physical and gynecological examination, measurement of the essential laboratory variables, and measurement of the fertility hormone levels.
resultsWithin 745 patients (mean age: 21.4±4.8), 276 patients were aged 12-18 years (group 1) and 469 patients were aged 22-28 years (group 2). Dehydroepiandrosterone sulfate (DHEA-S) (237.7 (22.6-721.5) vs. 162.5 (2.4- 660.7) respectively; p<0.001) was significantly higher in group 1 than group 2. There were 74 subjects (26.8%) with LH/FSH ratio > 2 in group 1 and 74 subjects (15.8%) with LH/FSH ratio > 2 in group 2 (p<0.001).
conclusionsBiochemical hyperandrogenism is much more valuable in adolescents than in young adult women for the diagnosis of PCOS. Biochemical hyperandrogenism should be tested in adolescents with menstrual irregularities.
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Registered trials
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