Evidence map›Paper›PMID 30581231›Full record

ArticleThe journal of extra-corporeal technology2018

An Ethanol-Free Autologous Thrombin System.

Andrea M Matuska, Marina K Klimovich, John R Chapman

Open access · bronzeAbstract read
In one paragraph

Article in The journal of extra-corporeal technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrea M MatuskaArthrex, Inc., Naples, Florida; and.
Marina K KlimovichArthrex, Inc., Naples, Florida; and.
John R ChapmanArthrex, Inc., Naples, Florida; and.
Arthrex (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombin is a coagulation protein of central importance to hemostasis and wound healing that can be sourced from human blood, bovine blood, and engineered cell lines. Only autologous thrombin lacks the risks of transmitting emergent pathogens or eliciting an immunogenic response. Previous commercial autologous thrombin devices require the use of high concentrations of ethanol to achieve thrombin stability, introducing cytotoxicity risks. A new point of care device for preparing an ethanol-free autologous thrombin serum was investigated. The ethanol-free autologous serum (AS) was prepared using the Thrombinator

Indexed as

Platelet-Rich PlasmaAnimalsBlood Coagulation TestsCattleEthanolHumansReproducibility of ResultsThrombinEthanolThrombinautologousblood-coagulationdevicefibrinplatelet rich plasmathrombin

Identifiers

PMID30581231
PMCPMC6296456
OpenAlexW3012460839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.