ArticleCurrent biology : CB2019
Retronasal Odor Perception Requires Taste Cortex, but Orthonasal Does Not.
Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- Recovery of Parosmia Preferentially Influences Longitudinal Improvement of Quality of Life in C19OD.International forum of allergy & rhinology · 2026Article
- Rapid odorant metabolism organizes identity- and timing-based odor representations by olfactory bulb inputs and outputs.bioRxiv : the preprint server for biology · 2026Article
- Olfactory-gustatory cross-modal integration: mechanisms of aroma-induced sweetness enhancement, sensory evaluation methodologies, neuroimaging evidence and advances in influencing factors.Journal of advanced research · 2026Review
- The Neural and Perceptual Effects of Stevia During Retronasal Occlusion.The European journal of neuroscience · 2026Article
- Electrochemical Sensors as a Tool for Taste Perception in Pharmaceutical Products: Advances and Perspectives.Biosensors · 2026Review
- Effect of Phenolic Compounds and Terpenes on the Flavour and Functionality of Plant-Based Foods.Nutrients · 2025Review
- Multi-Technique Flavoromics for Identifying Key Differential Volatile Compounds Underlying Sensory Profiles in Lager Beers.Foods (Basel, Switzerland) · 2025Article
- Tastes and retronasal odours evoke a shared flavour-specific neural code in the human insula.Nature communications · 2025Article
- Potential role of terpenes in recovery from olfactory dysfunction with olfactory training: a review.Molecular biology reports · 2025Review
- Coding odor modality in piriform cortex efficiently with low-dimensional subspaces: a shared covariance decoding approach.Biological cybernetics · 2025Article
- Mouthfeel of Food and Beverages: A Comprehensive Review of Physiology, Biochemistry, and Key Sensory Compounds.Comprehensive reviews in food science and food safety · 2025Review
- Gustatory cortex neurons perform reliability-dependent integration of multisensory flavor inputs.Current biology : CB · 2025Article
- Congruency of multisensory olfactory stimuli.Chemical senses · 2025Article
- Differences in hedonic perception of retronasal odors between young children and adults.Chemical senses · 2025Article
- Association between olfactory dysfunction and gustatory dysfunction: evidence from the National Health and Nutrition Examination Survey.Frontiers in public health · 2025Article
- Taste enhances the ability to express a preference for a congruent odor in rats.Behavioral neuroscience · 2024Article
- Multisensory Integration Underlies the Distinct Representation of Odor-Taste Mixtures in the Gustatory Cortex of Behaving Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- The effect of multisensory context and experience on flavor preference decisions in rats.Physiology & behavior · 2024Article
- An intra-oral flavor detection task in freely moving mice.iScience · 2024Article
- The role of the mediodorsal thalamus in chemosensory preference and consummatory behavior in rats.Chemical senses · 2024Article
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4 authors.
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Abstract
Smells can arise from a source external to the body and stimulate the olfactory epithelium upon inhalation through the nares (orthonasal olfaction). Alternatively, smells may arise from inside the mouth during consumption, stimulating the epithelium upon exhalation (retronasal olfaction). Both ortho- and retronasal olfaction produce highly salient percepts, but the two percepts have very different behavioral implications. Here, we use optogenetic manipulation in the context of a flavor preference learning paradigm to investigate differences in the neural circuits that process information in these two submodalities of olfaction. Our findings support a view in which retronasal, but not orthonasal, odors share processing circuitry commonly associated with taste. First, our behavioral results reveal that retronasal odors induce rapid preference learning and have a potentiating effect on orthonasal preference learning. Second, we demonstrate that inactivation of the insular gustatory cortex selectively impairs expression of retronasal preferences. Thus, orally sourced (retronasal) olfactory input is processed by a brain region responsible for taste processing, whereas externally sourced (orthonasal) olfactory input is not.
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