Evidence map›Paper›PMID 30580865›Full record

ReviewIndian heart journal

A critical analysis of the COMPASS trial with respect to benefit-risk assessment using the numbers needed to treat: Applicability and relevance in Indian patients with stable cardiovascular disease.

P Kerkar, D Bose, T Nishandar, G Sabnis, D Kumar, U M Thatte, N J Gogtay

Open access · goldAbstract readReview
In one paragraph

Review in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

P KerkarDepartments of Cardiology, Seth GS Medical College & KEM Hospital, Mumbai, 400012, India. Electronic address: prafullakerkar@rediffmail.com.
D BoseClinical Pharmacology, Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.
T NishandarClinical Pharmacology, Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.
G SabnisDepartments of Cardiology, Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.
D KumarDepartments of Cardiology, Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.
U M ThatteClinical Pharmacology, Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.
N J GogtayClinical Pharmacology, Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.
King Edward Memorial Hospital and Seth G.S. Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recently published Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial evaluated the hypothesis that rivaroxaban alone or in combination with aspirin would be more effective than aspirin alone for secondary prevention. In India, stable cardiovascular disease occurs in a much younger age group relative to the rest of the world. Our critical analysis of COMPASS trial showed that the younger age group appeared to derive greater benefit from the rivaroxaban+aspirin combination (relative to aspirin alone) as seen with number needed to treat metrics as compared to the older age group.

Indexed as

Risk AssessmentCardiovascular DiseasesFibrinolytic AgentsHumansIndiaMorbidityNumbers Needed To TreatSecondary PreventionThrombolytic TherapyFibrinolytic AgentsLikelihood of being helped and harmedRivaroxabanStable Coronary artery diseaseYoung Indian Population

Identifiers

PMID30580865
PMCPMC6306361
OpenAlexW2888176538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.