Evidence map›Paper›PMID 30580271›Full record

ArticleBMJ open2018

Feasibility and tolerability of bone impact microindentation testing: a cross-sectional, population-based study in Australia.

Pamela Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Mark A Kotowicz, Julie A Pasco

Abstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Associations between bone material strength index and FRAX scores.Journal of bone and mineral metabolism · 2025
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  3. Article
  4. Review
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  11. Treatments of osteoporosis increase bone material strength index in patients with low bone mass.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pamela Rufus-MembereSchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Kara L Holloway-KewSchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Adolfo Diez-PerezDepartment of Internal Medicine, Hospital del Mar-IMIM, Autonomous University of Barcelona and CIBERFES, Instituto Carlos III, Madrid, Spain.
Mark A KotowiczSchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Julie A PascoSchool of Medicine, Deakin University, Geelong, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe OsteoProbe measures Bone Material Strength Index (BMSi) of cortical bone in living humans using impact microindentation (IMI). Research using this minimally invasive technique is expanding yet, to-date, there have been no reports about its feasibility in the research setting. In this study, we assessed the feasibility and tolerability of using the OsteoProbe in men enrolled in the Geelong Osteoporosis Study.

designCross-sectional analysis of data collected in a population-based study.

settingBarwon Statistical Division, southeastern Australia, 2016-2018.

methodsFor 252 of 345 consecutive participants (ages 33-96 years), BMSi was measured using the OsteoProbe at the mid-tibia. Immediately following measurement, each participant used a Visual Analogue Scale (0-10) to rate the level of discomfort that was anticipated and experienced, their initial reluctance towards the measurement and their willingness to repeat measurement.

resultsReasons for non-measurement in 92 men were needle phobia (n=8), discomfort after first indentation (n=5), skin infections (n=21), excessive soft tissues around the mid-tibia region (n=56), inability to provide informed consent (n=2). Among 252 men who had IMI measures, the expectation for pain during measurement was low (1.54±1.56), as was actual pain experienced (0.38±0.71). Reluctance to undergo measurement was low (0.34±0.93). All participants indicated a willingness to have the measurement performed again. Mean (±SD) BMSi was 83.0±6.4 (range 62.3-93.0).

conclusionIn this study, the procedure was well accepted by participants suggesting that IMI testing with the OsteoProbe is feasible in a research setting.

Indexed as

Bone DensityCortical BoneOsteoporosisTibiaAdultAged, 80 and overAustraliaCross-Sectional StudiesFeasibility StudiesFemaleHumansMaleMiddle AgedOsteoporotic FracturesPatient PreferenceRisk Assessmentbone material strength indexfracturesmicroidentationOsteoProbe

Identifiers

PMID30580271
PMCPMC6318509

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.