Evidence map›Paper›PMID 30579424›Full record

ArticleThe Journal of investigative dermatology2019

Double-Stranded RNA Sensing Determines Epithelial Cell Identity.

Chung-Ping Liao, Edem Tchegnon, Lu Q Le

Abstract readComment
PubMed Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chung-Ping LiaoDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Edem TchegnonDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Integrative Molecular and Biomedical Sciences Program, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Lu Q LeDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Integrative Molecular and Biomedical Sciences Program, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA. Electronic address: Lu.Le@UTSouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin epithelium is constituted by heterogeneous keratinocytes in different body areas. In this issue, Zhou et al. used transcriptome analysis to investigate the site-specific epidermal cell identity on volar skin. Keratin 9 is highly enriched in volar keratinocytes, and its expression is dependent on low expression of the double-stranded RNA receptor DDX58, suggesting that double-stranded RNA sensing could allow a potential approach to modulate skin thickness and durability.

Indexed as

KeratinocytesRNA, Double-StrandedEpidermal CellsEpithelial CellsSkinRNA, Double-Stranded

Identifiers

PMID30579424
OpenAlexW2903850671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.