Evidence map›Paper›PMID 30579349›Full record

ArticleBMC anesthesiology2018

A comparison of postoperative outcomes with PDA ligation in the OR versus the NICU: a retrospective cohort study on the risks of transport.

Lisa K Lee, Michelle Y Woodfin, Marissa G Vadi, Tristan R Grogan, Phillip J Ross, Richard L Applegate, Marc Iravani

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lisa K LeeDepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, 757 Westwood Plaza, Suite 3325, Los Angeles, CA, 90095-7403, USA. lklee@mednet.ucla.edu.ORCID 0000-0001-5857-9260
Michelle Y WoodfinDepartment of Anesthesiology, Loma Linda University School of Medicine, Room 2532 LLUMC, 11234 Anderson Street, Loma Linda, CA, 92354, USA.
Marissa G VadiDepartment of Anesthesiology and Pain Medicine , Section of Pediatric Anesthesiology, University of California at Davis School of Medicine, PSSB Ste 1200, 4150 V Street, Sacramento, CA, 95817, USA.
Tristan R GroganDepartment of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, 911 Broxton Avenue, 3rd Floor, Los Angeles, CA, 90024, USA.
Phillip J RossDepartment of Anesthesiology, Loma Linda University School of Medicine, Room 2532 LLUMC, 11234 Anderson Street, Loma Linda, CA, 92354, USA.
Richard L ApplegateDepartment of Anesthesiology and Pain Medicine , Section of Pediatric Anesthesiology, University of California at Davis School of Medicine, PSSB Ste 1200, 4150 V Street, Sacramento, CA, 95817, USA.
Marc IravaniDepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, 757 Westwood Plaza, Suite 3325, Los Angeles, CA, 90095-7403, USA.
University of California, Los Angeles · USLoma Linda University Medical Center · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough patent ductus arteriosus (PDA) ligations in the Neonatal Intensive Care Unit (NICU) have been an accepted practice, many are still performed in the Operating Room (OR). Whether avoiding transport leads to improved perioperative outcomes is unclear. Here we aimed to determine whether PDA ligations in the NICU corresponded to higher risk of surgical site infection or mortality and if transport was associated with worsened perioperative outcomes.

methodsWe performed a retrospective cohort study of NICU patients, ≤37 weeks post-menstrual age, undergoing surgical PDA ligation in the NICU or OR. We excluded any infants undergoing device PDA closure. We measured the incidence of perioperative hypothermia, cardiac arrest, decreases in SpO2, hemodynamic instability and postoperative surgical site infection, sepsis and mortality.

resultsData was collected on 189 infants (100 OR, 89 NICU). After controlling for number of preoperative comorbidities, weight at time of procedure, procedure location and hospital in the mixed-effect model, no significant difference in mortality or sepsis was found (odds ratio 0.31, 95%CI 0.07, 1.30; p = 0.107, and odds ratio 0.40; 95%CI 0.14, 1.09; p = 0.072, respectively). There was an increased incidence of hemodynamic instability on transport postoperatively in the OR group (12.4% vs 2%, odds ratio 6.93; 95% CI 1.48, 35.52; p = 0.014).

conclusionPDA ligations in the NICU were not associated with higher incidences of surgical site infection or mortality. There was an increased incidence of hemodynamic instability in the OR group on transport back to the NICU. Larger multicenter studies following long-term outcomes are needed to evaluate the safety of performing all PDA ligations in the NICU.

Indexed as

Intensive Care Units, NeonatalOperating RoomsCohort StudiesDuctus Arteriosus, PatentFemaleHemodynamicsHumansInfant, NewbornLigationMalePatient TransferPostoperative PeriodRetrospective StudiesSurgical Wound InfectionTreatment OutcomeNeonatal intensive care unitNewborn infantPatent ductus arteriosusPostoperative period Hemodynamics.Surgical wound infection

Identifiers

PMID30579349
PMCPMC6303951
OpenAlexW2905933186

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.