ArticleNeuropsychologia2019
Dissociable medial temporal pathways for encoding emotional item and context information.
Article in Neuropsychologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cerebral Volumetric Correlates of Apathy in Alzheimer's Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort.Journal of Alzheimer's disease : JAD · 2022Pooled it
- Severe PTSD symptoms magnify episodic memory-encoding deficits and amygdala-ACC attenuation during unpredictable threat in male combat veterans.Molecular psychiatry · 2026Article
- Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis.Cognition · 2026Article
- Neurotransmitter-based machine-learning model for distinguishing Alzheimer's disease and mild cognitive impairment.The Journal of international medical research · 2026Article
- Semantic Dimensions Support the Cortical Representation of Object Memorability.Journal of cognitive neuroscience · 2025Article
- Animacy and threat influence location memory in adults.Memory & cognition · 2025Article
- Memory Boost for Recurring Emotional Events Is Driven by Initial Amygdala Response Promoting Stable Neocortical Patterns across Repetitions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Untangling the threads of motivated memory: Independent influences of reward and emotion.Psychonomic bulletin & review · 2025Article
- The emotion filmmaker: Temporal memory, time-emotion integration, and affective style.Emotion (Washington, D.C.) · 2024Article
- Age-related reduction in anxiety and neural encoding of negative emotional memory.Frontiers in aging neuroscience · 2024Article
- Does Expecting Matter? The Impact of Experimentally Established Expectations on Subsequent Memory Retrieval of Emotional Words.Journal of Intelligence · 2023Article
- Danger Changes the Way the Brain Consolidates Neutral Information; and Does So by Interacting with Processes Involved in the Encoding of That Information.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Category-specific memory encoding in the medial temporal lobe and beyond: the role of reward.Learning & memory (Cold Spring Harbor, N.Y.) · 2022Article
- An executive function subtype of PTSD with unique neural markers and clinical trajectories.Translational psychiatry · 2022Article
- Higher post-encoding cortisol benefits the selective consolidation of emotional aspects of memory.Neurobiology of learning and memory · 2021Article
- Amygdala and ventral tegmental area differentially interact with hippocampus and cortical medial temporal lobe during rest in humans.Hippocampus · 2020Article
- Reduced Memory Coherence for Negative Events and Its Relationship to Posttraumatic Stress Disorder.Current directions in psychological science · 2020Article
- Progression from Feature-Specific Brain Activity to Hippocampal Binding during Episodic Encoding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Cortico-hippocampal network connections support the multidimensional quality of episodic memory.eLife · 2019Article
- Increased Functional Coupling between VTA and Hippocampus during Rest in First-Episode Psychosis.eNeuroArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Emotional experiences are typically remembered with a greater sense of recollection than neutral experiences, but memory benefits for emotional items do not typically extend to their source contexts. Item and source memory have been attributed to different subregions of the medial temporal lobes (MTL), but it is unclear how emotional item recollection fits into existing models of MTL function and, in particular, what is the role of the hippocampus. To address these issues, we used high-resolution functional magnetic resonance imaging (fMRI) to examine MTL contributions to successful emotional item and context encoding. The results showed that emotional items were recollected more often than neutral items. Whereas amygdala and perirhinal cortex (PRC) activity supported the recollection advantage for emotional items, hippocampal and parahippocampal cortex activity predicted subsequent source memory for both types of items, reflecting a double dissociation between anterior and posterior MTL regions. In addition, amygdala activity during encoding modulated the relationships of PRC activity and hippocampal activity to subsequent item recollection and source memory, respectively. Specifically, whereas PRC activity best predicted subsequent item recollection when amygdala activity was relatively low, hippocampal activity best predicted source memory when amygdala activity was relatively high. We interpret these findings in terms of complementary compared to synergistic amygdala-MTL interactions. The results suggest that emotion-related enhancements in item recollection are supported by an amygdala-PRC pathway, which is separable from the hippocampal pathway that binds items to their source context.
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