ArticleThoracic cancer2019
Analysis of the associated factors for severe weight loss after minimally invasive McKeown esophagectomy.
Article in Thoracic cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Effect of ghrelin administration on postoperative inflammatory response and bodyweight loss in patients with oesophageal cancer undergoing oesophagectomy: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2023Pooled it
- Pre-Therapeutic Sarcopenia among Cancer Patients: An Up-to-Date Meta-Analysis of Prevalence and Predictive Value during Cancer Treatment.Nutrients · 2023Pooled it
- Article
- Association Between Taste Disorders and Malnutrition in Older Adults: A Scoping Review.Nutrition reviews · 2026Article
- Nasojejunal tube, jejunostomy tube, and fine needle catheter jejunostomy effects after esophagectomy.Frontiers in surgery · 2026Article
- Remission of type 2 diabetes one year after esophagectomy with gastric conduit reconstruction: A prospective cohort study.World journal of gastrointestinal surgery · 2025Article
- Association Between Body Composition and Survival in Patients With Gastroesophageal Adenocarcinoma: An Automated Deep Learning Approach.JCO clinical cancer informatics · 2024Article
- Prognostic Factors for Recovery from Left Recurrent Laryngeal Nerve Palsy After Minimally Invasive McKeown Esophagectomy: A Retrospective Study.Annals of surgical oncology · 2024Article
- Early implementation of a perioperative nutrition support pathway for patients undergoing esophagectomy for esophageal cancer.Cancer medicine · 2022Article
- Health-related quality of life after esophagectomy in patients with esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2022Review
- Nutritional assessment in esophageal fast-track surgery: comparisons of 4 objective malnutrition screening tools.Annals of translational medicine · 2022Article
- Functional syndromes and symptom-orientated aftercare after esophagectomy.Langenbeck's archives of surgery · 2021Review
- Outcomes of Esophageal Cancer after Esophagectomy in the Era of Early Injection Laryngoplasty.Diagnostics (Basel, Switzerland) · 2021Article
- Severe weight loss after minimally invasive oesophagectomy is associated with poor survival in patients with oesophageal cancer at 5 years.BMC gastroenterology · 2020Article
- Modified Collard versus end-to-side hand-sewn anastomosis for cervical anastomosis after McKeown esophagectomy.Thoracic cancer · 2020Article
- Risk factors of post-esophagectomy-induced malnutrition.Journal of thoracic disease · 2019Article
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study investigated the risk factors for severe weight loss (SWL) within one year after minimally invasive McKeown esophagectomy.
methodsEsophageal cancer patients who underwent McKeown esophagectomy between January and July 2017 were prospectively enrolled. Preoperative body weight (PBW) was chosen as the initial body weight.
resultsForty-four patients were enrolled and successfully followed up for one year. Median weight loss was 7.4% (quartile: 5.3-8.1%) and 12.6% (quartile: 8.8-17.7%) four weeks and one year after surgery, respectively. Accelerated weight loss occurred during the first two weeks after discharge, with median weight loss of 5.6% (quartile: 4.2-7.1%). Multivariable analysis showed that age ≥ 70 years (odds ratio [OR] 7.65; P = 0.030), preoperative sarcopenia (OR 7.18; P = 0.030), the first surgery in the daily schedule (OR 6.87; P = 0.032) and vocal cord paralysis (OR 12.30; P = 0.046) were independent risk factors for short-term (4 weeks) SWL (> 7.5% PBW), while an American Society of Anesthesiologists score of 3-4 (OR 6.58; P = 0.047), a high fat-free mass (OR 21.91; P = 0.003), and vocal cord paralysis (OR 25.83; P = 0.017) were independent risk factors for long-term (1 year) SWL (> 13.0% PBW) after esophagectomy. Postoperative symptoms of insomnia, appetite loss, dysphagia, eating difficulties, and taste issues were also related to SWL.
conclusionsIn esophageal cancer patients who have undergone esophagectomy, the first two weeks after hospital discharge is a key period for nutrition intervention. Patients with associated factors for SWL require postoperative nutrition support.
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