Evidence map›Paper›PMID 30578386›Full record

ArticleThe European respiratory journal2019

Association of outdoor temperature with lung function in a temperate climate.

Mary B Rice, Wenyuan Li, Elissa H Wilker, Diane R Gold, Joel Schwartz, Antonella Zanobetti, Petros Koutrakis, Itai Kloog, George R Washko, George T O'Connor and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The European respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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  9. Article
  10. Pulmonary function responses to extreme heat exposure in younger and older adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Mary B RiceDivision of Pulmonary, Critical Care and Sleep Medicine, Dept of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2538-391X
Wenyuan LiHarvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-6196-9964
Elissa H WilkerHarvard T.H. Chan School of Public Health, Boston, MA, USA.
Diane R GoldHarvard T.H. Chan School of Public Health, Boston, MA, USA.
Joel SchwartzHarvard T.H. Chan School of Public Health, Boston, MA, USA.
Antonella ZanobettiHarvard T.H. Chan School of Public Health, Boston, MA, USA.
Petros KoutrakisHarvard T.H. Chan School of Public Health, Boston, MA, USA.
Itai KloogDept of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel.
George R WashkoDivision of Pulmonary and Critical Care Medicine, Dept of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
George T O'ConnorThe NHLBI's Framingham Heart Study, Framingham, MA, USA.
Murray A MittlemanHarvard T.H. Chan School of Public Health, Boston, MA, USA.
Harvard University · USBen-Gurion University of the Negev · ILBeth Israel Deaconess Medical Center · USBoston University · USBrigham and Women's Hospital · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Marc G Weisskopf · 1985 to 2026
$44.6M
Air Pollution and the Lung in Health and COPD: Obstructive, Restrictive and Vascular PathwaysK23ES026204 · NIEHS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI RICE, MARY B · 2016 to 2020
$883k
NIEHS NIH HHS K23 ES026204NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

Acute exposure to cold dry air is a trigger of bronchoconstriction, but little is known about how daily outdoor temperature influences lung function.We investigated associations of temperature from a model using satellite remote sensing data with repeated measures of lung function among 5896 participants of the Framingham Heart Study Offspring and Third Generation cohorts residing in the Northeastern US. We further tested if temperature modified previously reported associations between pollution and lung function. We constructed linear mixed-effects models, and assessed departures from linearity using penalised splines.In fully adjusted linear models, 1-, 2- and 7-day average temperatures were all associated with lower lung function: each 5°C higher previous-week temperature was associated with a 20 mL lower (95% CI -34---6) forced expiratory volume in 1 s. There was significant effect modification by season: negative associations of temperature and lung function were present in winter and spring only. Negative associations between previous-day fine particulate matter and lung function were present during unseasonably warm but not unseasonably cool days, with a similar pattern for other pollutants.We speculate that temperature-related differences in lung function may be explained by behavioural changes on relatively warm days, which may increase outdoor exposures.

Indexed as

Forced Expiratory VolumeSeasonsTemperatureAdultAir PollutantsAir PollutionEnvironmental ExposureFemaleHumansLinear ModelsLongitudinal StudiesLungMaleMiddle AgedParticulate MatterUnited StatesAir PollutantsParticulate Matter

Identifiers

PMID30578386
PMCPMC6903481
OpenAlexW2906444262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.