Evidence map›Paper›PMID 30577839›Full record

ArticleBMC bioinformatics2018

Bidirectional long short-term memory with CRF for detecting biomedical event trigger in FastText semantic space.

Yan Wang, Jian Wang, Hongfei Lin, Xiwei Tang, Shaowu Zhang, Lishuang Li

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Article in BMC bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Yan WangSchool of Computer Science and Technology, Dalian University of Technology, Dalian, China.
Jian WangSchool of Computer Science and Technology, Dalian University of Technology, Dalian, China. wangjian@dlut.edu.cn.
Hongfei LinSchool of Computer Science and Technology, Dalian University of Technology, Dalian, China.
Xiwei TangSchool of Information Science and Engineering, Hunan First Normal University, Changsha, China. tangxiwei2010@gmail.com.
Shaowu ZhangSchool of Computer Science and Technology, Dalian University of Technology, Dalian, China.
Lishuang LiSchool of Computer Science and Technology, Dalian University of Technology, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn biomedical information extraction, event extraction plays a crucial role. Biological events are used to describe the dynamic effects or relationships between biological entities such as proteins and genes. Event extraction is generally divided into trigger detection and argument recognition. The performance of trigger detection directly affects the results of the event extraction. In general, the traditional method is used to address the trigger detection as a classification task, as well as the use of machine learning or rules method, which construct many features to improve the classification results. Moreover, the classification model only recognizes triggers composed of single words, whereas for multiple words, the result is unsatisfactory.

resultsThe corpus of our model is MLEE. If we were to only use the biomedical LSTM and CRF model without other features, the F-score would reach about 78.08%. Comparing entity to part of speech (POS), we find the entity features more conducive to the improvement of performance of detection, with the F-score potentially reaching about 80%. Furthermore, we also experiment on the other three corpora (BioNLP 2009, BioNLP 2011, and BioNLP 2013) to verify the generalization of our model. Hence, F-scores can reach more than 60%, which are better than the comparative experiments.

conclusionsThe trigger recognition method based on the sequence annotation model does not require initial complex feature engineering, and only requires a simple labeling mechanism to complete the training. Therefore, generalization of our model is better compared to other traditional models. Secondly, this method can identify multi-word triggers, thereby improving the F-scores of trigger recognition. Thirdly, details on the entity have a crucial impact on trigger detection. Finally, the combination of character-level word embedding and word-level word embedding provides increasingly effective information for the model; therefore, it is a key to the success of the experiment.

Indexed as

AlgorithmsBiomedical ResearchSemanticsInformation Storage and RetrievalMachine LearningBidirectional LSTMBiomedical eventsCRFFastTextSemantic spaceTrigger detection

Identifiers

PMID30577839
PMCPMC6302454

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.