Evidence map›Paper›PMID 30577674›Full record

ArticleSensors (Basel, Switzerland)2018

Effective Construction of a High-Capacity Boronic Acid Layer on a Quartz Crystal Microbalance Chip for High-Density Antibody Immobilization.

Pei-Heng Lin, Sheng-Cih Huang, Kuang-Po Chen, Bor-Ran Li, Yaw-Kuen Li

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pei-Heng LinInstitute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan. pamela.eed06g@nctu.edu.tw.
Sheng-Cih HuangDepartment of Applied Chemistry, College of Science, National Chiao Tung University, Hsinchu 30010, Taiwan. Shengcih.bt96g@nctu.edu.tw.
Kuang-Po ChenDepartment of Applied Chemistry, College of Science, National Chiao Tung University, Hsinchu 30010, Taiwan. guangbo@g2.nctu.edu.tw.ORCID 0000-0002-8557-6097
Bor-Ran LiInstitute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan. liborran@g2.nctu.edu.tw.
Yaw-Kuen LiDepartment of Applied Chemistry, College of Science, National Chiao Tung University, Hsinchu 30010, Taiwan. ykl@g2.nctu.edu.tw.
National Yang Ming Chiao Tung University · TW

Funding

Minister of Science and Technology of Taiwan 106-2113-M-009-013-MY2Minister of Science and Technology of Taiwan MOST 105-2113-M-009-005
6 · The paper itself

Abstract

Boronic acids (BAs) provide strong potential in orientation immobilization of antibody and the modification method is crucial for efficiency optimization. A highly effective method has been developed for rapid antibody immobilization on gold electrodes through the electrodeposition of a BA⁻containing linker in this study. Aniline-based BA forms a condense layer while antibody could automatically immobilize on the surface of the electrode. Compare to traditional self-assembled monolayer method, the electrodeposition process dramatically reduces the modification time from days to seconds. It also enhances the immobilized efficiency from 95 to 408 (ng/cm²) with a strong preference being exhibited for shorter aniline-based linkers.

Indexed as

Biosensing TechniquesQuartz Crystal Microbalance TechniquesAdsorptionAniline CompoundsAntibodies, ImmobilizedBoronic AcidsElectrodesGoldHumansanilineAniline CompoundsAntibodies, ImmobilizedBoronic AcidsGoldboronic acidelectrodepositionorientated antibody immobilizationquartz crystal microbalance

Identifiers

PMID30577674
PMCPMC6339082
OpenAlexW2906262383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.