Evidence map›Paper›PMID 30577575›Full record

ArticleVaccines2018

The Modified Vaccination Technique.

Arpad Barabas, Chad Cole, Zoltan Kovacs, Erno Kovacs, Rene Lafreniere

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 31 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Arpad BarabasDepartment of Surgery, University of Calgary, Calgary, AB T2N 1N4, Canada. barabas@ucalgary.ca.ORCID 0000-0002-4238-9750
Chad ColeDepartment of Neurosurgery, University of Utah, Salt Lake City, Utah, UT 84112, USA. Cole.nsgy@gmail.com.
Zoltan KovacsDepartment of Surgery, University of Calgary, Calgary, AB T2N 1N4, Canada. kovacsz@ucalgary.ca.
Erno KovacsDepartment of Medical Genetics, University of Calgary, Calgary, AB T2N 1N4, Canada. erno.kovacs@ucalgary.ca.
Rene LafreniereDepartment of Surgery, University of Calgary, Calgary, AB T2N 1N4, Canada. rlafreni@ucalgary.ca.
University of Calgary · CAUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to active and passive immunizations, there is a third method of immunization, the modified vaccination technique, which is based on injecting a combination of target antigens and antibodies against this antigen. The vaccine is essentially comprised of immune complexes with pre-determined immune-inducing components. When such an immune complex (target antigen × antibody against the target antigen) with a slight antigen excess is administered, it evokes a corrective immune response by the production of the same antibody with the same specificity against the target antigen that is present in the immune complex (pre-determined immune response).

Indexed as

antibody information transferHeymann nephritisimmune complex

Identifiers

PMID30577575
PMCPMC6466438
OpenAlexW2903752946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.