Evidence map›Paper›PMID 30577497›Full record

ArticleInternational journal of molecular sciences2018

Olive Oil, Palm Oil, and Hybrid Palm Oil Distinctly Modulate Liver Transcriptome and Induce NAFLD in Mice Fed a High-Fat Diet.

Rafael C Sales, Priscylla C Medeiros, Flavia Spreafico, Patrícia C de Velasco, Fernanda K A Gonçalves, Roberto Martín-Hernández, Diana C Mantilla-Escalante, Judit Gil-Zamorano, Wilza A F Peres, Sergio A L de Souza and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 52 citations in OpenAlex.

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  9. Nutrition Genomics.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Rafael C SalesInstituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil. c.sales.rafael@gmail.com.ORCID 0000-0002-6005-1438
Priscylla C MedeirosFaculdade de Medicina, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21044-020, Brazil. pri.biomed3@gmail.com.ORCID 0000-0002-5389-0006
Flavia SpreaficoInstituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil. flaviasfer@gmail.com.ORCID 0000-0001-8956-5718
Patrícia C de VelascoInstituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil. patriciac.velasco@gmail.com.ORCID 0000-0001-8956-5718
Fernanda K A GonçalvesInstituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil. fernandakgst@gmail.com.
Roberto Martín-HernándezGENYAL Platform on Nutrition and Health, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, 28049 Madrid, Spain. roberto.martin@imdea.org.
Diana C Mantilla-EscalanteLaboratory of Epigenetics of Lipid Metabolism, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, 28049 Madrid, Spain. diana.mantilla@imdea.org.
Judit Gil-ZamoranoLaboratory of Epigenetics of Lipid Metabolism, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, 28049 Madrid, Spain. judit.gil@imdea.org.
Wilza A F PeresInstituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil. wilza@nutricao.ufrj.br.
Sergio A L de SouzaFaculdade de Medicina, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21044-020, Brazil. sergioalsouza@gmail.com.ORCID 0000-0002-5389-0006
Alberto DávalosLaboratory of Epigenetics of Lipid Metabolism, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, 28049 Madrid, Spain. alberto.davalos@imdea.org.
Maria G Tavares do CarmoInstituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, Brazil. tcarmo@editema.com.br.ORCID 0000-0003-1376-1098
Universidade Federal do Rio de Janeiro · BRMadrid Institute for Advanced Studies · ES

Funding

Agencia Estatal de Investigación and European FEDER Funds AGL2016-78922-RConselho Nacional de Desenvolvimento Científico e Tecnológico 305329/2016-2Coordenação de Aperfeicoamento de Pessoal de Nível Superior (CAPES) Postgraduate scholarship to RCS (Finance Code 001)Fundação de Amparo a Pesquisa do Rio de Janeiro (FAPERJ) E-26/111.725/2013Fundación Ramón Areces CIVP18A3888
6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is highly prevalent worldwide. The most severe form is nonalcoholic steatohepatitis (NASH). Among risk factors for the development of NAFLD is excessive lipid intake. Since palm (P) oil is the most consumed oil in the world, we aimed to investigate the effects of high-fat diets made with P oil, hybrid palm (HP) oil, or olive (O) oil in liver. Twenty-four male mice (C57Bl/6J) were fed a high-fat diet (41% fat) containing P, HP, or O oils for 8 weeks and compared to a control (C) group fed a chow diet. Adiposity was measured with computed tomography. Body, adipose tissue, and liver weights, as well as liver fat (Bligh⁻Dyer), blood lipid profile, glucose, and liver enzymes were measured. Liver histology (hematoxylin⁻eosin) and transcriptome (microarray-based) were performed. ANOVA tests with Newman⁻Keuls were used. Body weight was increased in the P group (

Indexed as

TranscriptomeAdipose TissueAdiposityAnimalsBiopsyBody WeightDiet, High-FatGene Expression ProfilingLipid MetabolismLiverLiver Function TestsMaleMiceNon-alcoholic Fatty Liver DiseaseOlive OilPalm OilOlive OilPalm OilPlant Oilshigh-fat diethybrid palm oilNAFLDNASHolive oilpalm oiltranscriptomics

Identifiers

PMID30577497
PMCPMC6337378
OpenAlexW2903590673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.