Evidence map›Paper›PMID 30577445›Full record

ReviewNutrients2018

A Guide to Applying the Sex-Gender Perspective to Nutritional Genomics.

Dolores Corella, Oscar Coltell, Olga Portolés, Mercedes Sotos-Prieto, Rebeca Fernández-Carrión, Judith B Ramirez-Sabio, Vicente Zanón-Moreno, Josiemer Mattei, José V Sorlí, Jose M Ordovas

Abstract readReview
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Guidelines on the use of sex and gender in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Sex and age differences in attitudes and intention to adopt personalised nutrition in a UK sample.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2021
    Article
  16. The Person's Care Requires a Sex and Gender Approach.Journal of clinical medicine · 2021
    Review
  17. Functional Meat Products as Oxidative Stress Modulators: A Review.Advances in nutrition (Bethesda, Md.) · 2021
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dolores CorellaCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain. Dolores.corella@uv.es.ORCID 0000-0002-2366-4104
Oscar ColtellCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain. oscar.coltell@uji.es.ORCID 0000-0002-4518-8495
Olga PortolésCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain. Olga.Portoles@uv.es.
Mercedes Sotos-PrietoSchool of Applied Health Sciences and Wellness, Ohio University, Athens, OH 45701, USA. sotospri@ohio.edu.
Rebeca Fernández-CarriónCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain. Rebeca.Fernandez@uv.es.
Judith B Ramirez-SabioOncology Department, Sagunto Hospital, 46500 Sagunto, Spain. jbramire@uv.es.
Vicente Zanón-MorenoOphthalmology Research Unit "Santiago Grisolia", Dr. Peset University Hospital, 46017 Valencia, Spain. Vicente.Zanon-Moreno@uv.es.ORCID 0000-0003-1179-1592
Josiemer MatteiDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. jmattei@hsph.harvard.edu.ORCID 0000-0001-5424-8245
José V SorlíCIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain. jose.sorli@uv.es.
Jose M OrdovasNutrition and Genomics Laboratory, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111 USA. jose.ordovas@tufts.edu.

Funding

Fundació La Marató de TV3 538/U/2016Generalitat Valenciana PROMETEO2017/017Real Colegio Complutense at Harvard University Dolores CorellaSpanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) CIBER 06/03Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) PI06/1326Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) PI16/00366Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) PRX17/00500Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economía y Competitividad-Fondo Europeo de Desarrollo Regional (FEDER) SAF2016-80532-RUniversity Jaume I COGRUP/2016/06University Jaume I P1-1B2013-54
6 · The paper itself

Abstract

Precision nutrition aims to make dietary recommendations of a more personalized nature possible, to optimize the prevention or delay of a disease and to improve health. Therefore, the characteristics (including sex) of an individual have to be taken into account as well as a series of omics markers. The results of nutritional genomics studies are crucial to generate the evidence needed so that precision nutrition can be applied. Although sex is one of the fundamental variables for making recommendations, at present, the nutritional genomics studies undertaken have not analyzed, systematically and with a gender perspective, the heterogeneity/homogeneity in gene-diet interactions on the different phenotypes studied, thus there is little information available on this issue and needs to be improved. Here we argue for the need to incorporate the gender perspective in nutritional genomics studies, present the general context, analyze the differences between sex and gender, as well as the limitations to measuring them and to detecting specific sex-gene or sex-phenotype associations, both at the specific gene level or in genome-wide-association studies. We analyzed the main sex-specific gene-diet interactions published to date and their main limitations and present guidelines with recommendations to be followed when undertaking new nutritional genomics studies incorporating the gender perspective.

Indexed as

Sex FactorsDietFemaleGender IdentityHumansMaleNutrigenomicsNutritional Physiological PhenomenaNutritional StatusPhenotypePrecision MedicineSex Characteristicsdietgendernutrigenomicsnutritional genomicsprecision nutritionsex

Identifiers

PMID30577445
PMCPMC6357147

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.