Evidence map›Paper›PMID 30577438›Full record

ArticleMarine drugs2018

Spinochrome D Attenuates Doxorubicin-Induced Cardiomyocyte Death via Improving Glutathione Metabolism and Attenuating Oxidative Stress.

Chang Shin Yoon, Hyoung Kyu Kim, Natalia P Mishchenko, Elena A Vasileva, Sergey A Fedoreyev, Valentin A Stonik, Jin Han

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  10. Yang-xin-xue keli exerts therapeutic effectsFrontiers in pharmacology · 2022
    Article
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  18. Metabolomic Perspectives in Antiblastic Cardiotoxicity and Cardioprotection.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chang Shin YoonNational Research Laboratory for Mitochondrial Signaling, Department of Physiology, College of Medicine, Cardiovascular and Metabolic Disease Center (CMDC), Inje University, Busan 614-735, Korea. changshin73@gmail.com.ORCID 0000-0003-0300-5184
Hyoung Kyu KimNational Research Laboratory for Mitochondrial Signaling, Department of Physiology, College of Medicine, Cardiovascular and Metabolic Disease Center (CMDC), Inje University, Busan 614-735, Korea. estrus74@gmail.com.
Natalia P MishchenkoG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, Vladivostok 690022, Russia. mischenkonp@mail.ru.ORCID 0000-0001-7616-574X
Elena A VasilevaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, Vladivostok 690022, Russia. vasilieva_el_an@mail.ru.
Sergey A FedoreyevG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, Vladivostok 690022, Russia. fedoreev-s@mail.ru.
Valentin A StonikG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Science, Vladivostok 690022, Russia. stonik@piboc.dvo.ru.
Jin HanNational Research Laboratory for Mitochondrial Signaling, Department of Physiology, College of Medicine, Cardiovascular and Metabolic Disease Center (CMDC), Inje University, Busan 614-735, Korea. phyhanj@inje.ac.kr.
Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RUInje University · KR

Funding

Ministry of Education, Science and Technology 2010-0020224, 2018R1D1A1A09081767, 2017K1A3A1A49070056
6 · The paper itself

Abstract

Doxorubicin, an anthracycline from

Indexed as

AnimalsAntibiotics, AntineoplasticApoptosisCardiotonic AgentsCardiotoxicityCell SurvivalDoxorubicinFemaleGlutathioneHeLa CellsHumansMCF-7 CellsMembrane Potential, MitochondrialMetabolomicsMitochondriaMyocytes, CardiacAntibiotics, AntineoplasticCardiotonic AgentsDoxorubicinGlutathioneNaphthoquinonesReactive Oxygen Speciesspinochrome Acardioprotective effectdoxorubicinSpinochrome D

Identifiers

PMID30577438
PMCPMC6356724
OpenAlexW2903862582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.