Evidence map›Paper›PMID 30577236›Full record

ReviewTransplantation proceedings2018

Review: The Perioperative Use of Thromboelastography for Liver Transplant Patients.

R B Hawkins, S L Raymond, T Hartjes, P A Efron, S D Larson, K A Andreoni, E M Thomas

Open access · greenAbstract readReview
In one paragraph

Review in Transplantation proceedings, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Refractory thrombocytopenia during liver transplantation requiring splenectomy.Proceedings (Baylor University. Medical Center) · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Clinical Considerations of Coagulopathy in Acute Liver Failure.Journal of clinical and translational hepatology · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

R B HawkinsDepartment of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
S L RaymondDepartment of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
T HartjesDepartment of Surgery, University of Florida College of Medicine, Gainesville, FL, USA; University of Florida College of Nursing, Gainesville, FL, USA.
P A EfronDepartment of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
S D LarsonDepartment of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
K A AndreoniDepartment of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
E M ThomasDepartment of Surgery, University of Florida College of Medicine, Gainesville, FL, USA. Electronic address: Elizabeth.Thomas@surgery.ufl.edu.
Florida College · USUniversity of Florida · US

Funding

Molecular Biology in Burns and TraumaT32GM008721 · NIGMS · UNIVERSITY OF FLORIDA · PI Philip A Efron · 1999 to 2026
$5.0M
NIGMS NIH HHS T32 GM008721
6 · The paper itself

Abstract

Thromboelastography (TEG) is a viscoelastic test that allows rapid evaluation of clot formation and fibrinolysis from a sample of whole blood. TEG is increasingly utilized to guide blood product resuscitation in surgical patients and transfusions for liver transplant patients. Patients with severe liver failure have significant derangement of their clotting function due to impaired production of procoagulant and anticoagulant factors. Traditional coagulation studies are limited by the short time needed for the result and provide little information about the dynamics and strength of clot formation. In addition, traditional coagulation studies do not correlate well with bleeding episodes and may lead to over-transfusion of various blood products. Evidence is less robust regarding the use of TEG for transfusion management decisions in severe liver failure patients awaiting, undergoing, or immediately after liver transplant surgery. However, the available evidence suggests that systematic implementation of TEG rather than traditional coagulation studies results in the administration of fewer blood products without increased mortality or complications. The purpose of this study is to review the literature regarding the use of TEG in liver failure patients prior to liver transplant, intraoperatively, and postoperatively. Additional high-quality randomized controlled studies should be performed to evaluate the use of TEG to guide transfusion decisions, particularly in the postoperative period following liver transplantation.

Indexed as

FemaleHumansLiver TransplantationMiddle AgedThrombelastography

Identifiers

PMID30577236
PMCPMC12451651
OpenAlexW2886451570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.