Evidence map›Paper›PMID 30576921›Full record

ReviewRedox biology2019

Strategies to detect mitochondrial oxidants.

Alicia J Kowaltowski

Abstract readReview
In one paragraph

Review in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Small molecule probes for peroxynitrite detection.Redox biochemistry and chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Alicia J KowaltowskiDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, Cidade Universitária, São Paulo, SP 05508-000, Brazil. Electronic address: alicia@iq.usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial oxidants (or reactive oxygen species) participate in a myriad of physiological and pathological processes. They are, however, quite hard to measure due to their chemical nature and specific subcellular location. Here, we review techniques to measure mitochondrial oxidants in biological systems as well as the results of their activity, highlighting conditions to be considered, controls and recommended practices. We will delineate experimental setups that use combined strategies to convincingly demonstrate the biological effects of mitochondrial oxidants, using the imperfect methodology available today.

Indexed as

AnimalsAntioxidantsBiological AssayHumansMitochondriaModels, AnimalMolecular ProbesOxidantsOxidative StressReactive Oxygen SpeciesAntioxidantsMolecular ProbesOxidantsReactive Oxygen SpeciesMethodsMitochondriaOxidantsProbesReactive oxygen species

Identifiers

PMID30576921
PMCPMC6302213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.