Evidence map›Paper›PMID 30576628›Full record

ReviewArchives of biochemistry and biophysics2019

Lost in translation: Interpreting cardiac muscle mechanics data in clinical practice.

Ranganath Mamidi, Jiayang Li, Chang Yoon Doh, Joshua B Holmes, Julian E Stelzer

Abstract readReview
In one paragraph

Review in Archives of biochemistry and biophysics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Current and Future Directions of Myofilament Regulation.Archives of biochemistry and biophysics · 2019
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ranganath MamidiDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Jiayang LiDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Chang Yoon DohDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Joshua B HolmesDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Julian E StelzerDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA. Electronic address: julian.stelzer@case.edu.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
TISSUE CULTURE AND HYBRIDOMA MODULEP30EY011373 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI Irina A Pikuleva · 1997 to 2026
$17.7M
BIOMETRIC-GENETIC ANALYSIS OF CARDIOVASCULAR DISEASET32HL007567 · NHLBI · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI ZHU, XIAOFENG · 1985 to 2021
$6.0M
Functional consequences of FHC mutations in cardiac MyBPCR01HL114770 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI STELZER, JULIAN · 2013 to 2023
$4.3M
NRSA Training CoreTL1TR002549 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI HARDING, CLIFFORD V · 2018 to 2022
$2.9M
High resolution ultrasound for small animal imagingS10OD021635 · OD · CASE WESTERN RESERVE UNIVERSITY · PI STELZER, JULIAN · 2016 to 2016
$478k
NCATS NIH HHS TL1 TR002549NEI NIH HHS P30 EY011373NHLBI NIH HHS R01 HL114770NHLBI NIH HHS T32 HL007567NIGMS NIH HHS T32 GM007250NIH HHS S10 OD021635
6 · The paper itself

Abstract

Current inotropic therapies improve systolic function in heart failure patients but also elicit undesirable side effects such as arrhythmias and increased intracellular Ca

Indexed as

MyocardiumTranslational Research, BiomedicalAnimalsCardiotonic AgentsHeart FailureHumansMyocardial ContractionSarcomeresCardiotonic AgentsBiophysical measurementsCross-bridge behaviorFailing myocardiumIn vivo functionMyosin modulatorsSarcomere-based therapies

Identifiers

PMID30576628
PMCPMC6345594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.