ArticleOrganic letters2019
Photoinitiated Three-Component α-Perfluoroalkyl-β-heteroarylation of Unactivated Alkenes via Electron Catalysis.
Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Efficient Approaches to Six-Membered Polyazacyclic Compounds-Part 3: C-H Functionalization of Heterocycles.Molecules (Basel, Switzerland) · 2026Review
- Recent Advances in Visible Light-Induced C-H Functionalization of Imidazo[1,2-a]pyridines.Molecules (Basel, Switzerland) · 2025Review
- Ni-Catalyzed Regioselective Alkylarylation of Unactivated Alkenes in Amines Enabled by Cooperative Ligand Effects of Nitriles and Electron-Deficient Alkenes.Journal of the American Chemical Society · 2025Article
- Recent Developments in Direct C-H Functionalization of Quinoxalin-2(1Molecules (Basel, Switzerland) · 2023Review
- Article
- Metal-free visible-light-induced hydroxy-perfluoroalkylation of conjugated olefins using enamine catalyst.RSC advances · 2022Article
- A general electron donor-acceptor complex for photoactivation of arenesChemical science · 2022Article
- Allylboronic Esters as Acceptors in Radical Addition, Boron 1,2-Migration, and Trapping Cascades.Organic letters · 2022Article
- Radical chain monoalkylation of pyridines.Chemical science · 2021Article
- Metal-Free Direct C-H Functionalization of Quinoxalin-2(1Frontiers in chemistry · 2021Article
- Visible-Light Photoredox-Catalyzed Amidation of Benzylic Alcohols.The Journal of organic chemistry · 2020Article
- Photoinitiated decarboxylative C3-difluoroarylmethylation of quinoxalin-2(1RSC advances · 2020Article
- Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBDFrontiers in chemistry · 2020Article
- The C3-H Bond Functionalization of Quinoxalin-2(1Frontiers in chemistry · 2020Review
- Alkyl Radical Addition to Aliphatic and AromaticOrganic letters · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A visible-light-initiated α-perfluoroalkyl-β-heteroarylation of various alkenes with perfluoroalkyl iodides and quinoxalin-2(1 H)-ones is presented. This three-component radical cascade reaction allows an efficient synthesis of a range of perfluoroalkyl containing quinoxalin-2(1 H)-one derivatives in moderate to excellent yields under mild conditions. Reactions proceed via acidic aminyl radicals that are readily deprotonated to give the corresponding radical anions able to sustain the radical chain as single electron transfer reducing reagents. Hence, the overall cascade classifies as an electron-catalyzed process.
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Registered trials
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