ArticleEuropean journal of immunology2019
IL-4 promotes stromal cell expansion and is critical for development of a type-2, but not a type 1 immune response.
Article in European journal of immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Engineering Adaptive Immunity in 3D: A Patient-Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- IL-4 impairs the formation of skin-resident memory CD8Nature immunology · 2025Article
- Yavar-70A, a novel water-in-oil adjuvant: A potency study in HPV-16E7d vaccine model.Iranian journal of basic medical sciences · 2025Article
- Maternal Helminth Infection Causes Dysfunctional B Cell Development in Male Offspring.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
- IL-4 modified expanded polytetrafluoroethylene (e-PTFE) surgical patch promotes angiogenesis in transplanted flap and inhibits inflammatory response.BMC surgery · 2023Article
- Immune changes in hilar tumor draining lymph nodes following node sparing neoadjuvant chemoradiotherapy of localized cN0 non-small cell lung cancer.Frontiers in oncology · 2023Article
- Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation.Immunity · 2021Article
- Application of TGF-β1, TIMP-1 and TIMP-2 small interfering RNAs can alleviate CClExperimental and therapeutic medicine · 2021Article
- Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities.Cell and tissue research · 2021Review
- Maternal schistosomiasis impairs offspring Interleukin-4 production and B cell expansion.PLoS pathogens · 2021Article
- Selenium-Containing Amino Acids Protect Dextran Sulfate Sodium-Induced Colitis via Ameliorating Oxidative Stress and Intestinal Inflammation.Journal of inflammation research · 2021Article
- Defined Intestinal Regions Are Drained by Specific Lymph Nodes That Mount Distinct Th1 and Th2 Responses AgainstFrontiers in immunology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
IL-4 is critical for differentiation of Th2 cells and antibody isotype switching, but our work demonstrated that it is produced in the peripheral LN under both Type 2, and Type 1 conditions, raising the possibility of other functions. We found that IL-4 is vital for proper positioning of hematopoietic and stromal cells in steady state, and the lack of IL-4 or IL-4Rα correlates with disarrangement of both follicular dendritic cells and CD31
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Registered trials
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