ArticleJournal of occupational and environmental medicine2019
Risk Factors and Mechanisms Underlying Cross-Shift Decline in Kidney Function in Guatemalan Sugarcane Workers.
Article in Journal of occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
59 citing papers in PubMed, 83 citations in OpenAlex.
- Longitudinal assessment of kidney function in migrant farm workers.Environmental research · 2021Trial
- Trends in Occupational Heat-Health Research in Low-and Middle-Income Countries: A Mapping Review.Current environmental health reports · 2026Review
- Environmental and occupational exposures for chronic kidney disease of unknown aetiology (CKDu): field investigations in rural Sri Lanka.BMC public health · 2026Article
- Climate Change, Environmental Risk Factors, and Gout.Arthritis care & research · 2026Review
- The association between shift work, occupational physical activity and cardiovascular-kidney-metabolic syndrome: a cohort study in China.Frontiers in public health · 2026Article
- Evaluating the effects of heat strain and air pollution on kidney health.Environment international · 2026Article
- Association between job characteristics and kidney function among men: a cross-sectional analysis of the Rafsanjan cohort study.BMC nephrology · 2025Article
- Longitudinal associations and interactions of heat and metal(loid) exposure with kidney outcomes in Mexican agricultural workers.Environmental research · 2025Article
- Biomarkers of Kidney Function and Injury Across Fire Seasons and During a Mid-Season Fire Incident in the Wildland Firefighter Exposure and Health Effect (WFFEHE) Study.American journal of industrial medicine · 2025Article
- Longitudinal Estimated GFR Trajectories Among Workers at High Risk for CKD of Unknown Etiology.Kidney international reports · 2025Article
- Article
- Rest, shade, hydration and hygiene for the prevention of kidney injuries and inflammation in a Nicaraguan sugarcane worker cohort.Occupational and environmental medicine · 2025Article
- Work and work exposures in sugarcane farming in Eswatini, Southern Africa.International archives of occupational and environmental health · 2025Article
- The work-recovery cycle of kidney strain and inflammation in sugarcane workers following repeat heat exposure at work and at home.European journal of applied physiology · 2025Article
- Effects of heavy metal exposure on kidney transplant recipients: mechanisms and clinical implications for graft failure risk.Frontiers in immunology · 2025Review
- A Systems-Based Approach for the Prevention of Heat-Associated Kidney Disease in Latin American Workers.Annals of global health · 2025Article
- A longitudinal assessment of heat exposure and biomarkers of kidney function on heat shock protein 70 and antibodies among agricultural workers.BMC nephrology · 2024Article
- Emerging Roles of Xanthine Oxidoreductase in Chronic Kidney Disease.Antioxidants (Basel, Switzerland) · 2024Review
- Exposome and Metabolome Analysis of Sugarcane Workers Reveals Predictors of Kidney Injury.Kidney international reports · 2024Article
- Health burden of sugarcane burning on agricultural workers and nearby communities.Inhalation toxicology · 2024Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 3 countries.
Funding
Abstract
objectiveIdentify early biomarkers and mechanisms of acute kidney injury in workers at risk of developing chronic kidney disease of unknown origin (CKDu).
methodsWe assessed cross-shift changes in kidney function and biomarkers of injury in 105 healthy sugarcane workers. We obtained pre-harvest clinical data as well as daily environmental, clinical, and productivity data for each worker.
resultsThe average percent decline in cross-shift estimated glomerular filtration rate (eGFR) was 21.8% (standard deviation [SD] 13.6%). Increasing wet bulb globe temperature (WBGT), high uric acid, decreased urine pH, urinary leukocyte esterase, and serum hyperosmolality were risk factors for decline in kidney function.
conclusionsSugarcane workers with normal kidney function experience recurrent subclinical kidney injury, associated with elevations in biomarkers of injury that suggest exposure to high temperatures and extreme physical demands.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.