Evidence map›Paper›PMID 30575526›Full record

ArticleIEEE transactions on bio-medical engineering2019

Development of Algorithms for Automated Detection of Cervical Pre-Cancers With a Low-Cost, Point-of-Care, Pocket Colposcope.

Mercy Nyamewaa Asiedu, Anish Simhal, Usamah Chaudhary, Jenna L Mueller, Christopher T Lam, John W Schmitt, Gino Venegas, Guillermo Sapiro, Nimmi Ramanujam

Open access · bronzeAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 110 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Deep dive into deep learning methods for cervical cancer detection and classification.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Speculum-free portable preterm imaging system.Journal of biomedical optics · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Mercy Nyamewaa Asiedu
Anish Simhal
Usamah Chaudhary
Jenna L Mueller
Christopher T Lam
John W Schmitt
Gino Venegas
Guillermo Sapiro
Nimmi Ramanujam
Duke University · USDuke Medical Center · USLiga Contra el Cancer · PE

Funding

Novel see and treat strategies for cervical cancer prevention in low-resource settingsR01CA239268 · NCI · DUKE UNIVERSITY · PI KATZ, DAVID FRANK, RAMANUJAM, NIRMALA · 2019 to 2023
$3.1M
Culturally appropriate screening and diagnosis of cervical cancer in East AfricaR01CA193380 · NCI · DUKE UNIVERSITY · PI RAMANUJAM, NIRMALA · 2015 to 2019
$2.9M
A Viable Solution for a See and Treat Paradigm for Cervical Pre-cancer in AfricaR01CA195500 · NCI · DUKE UNIVERSITY · PI RAMANUJAM, NIRMALA · 2015 to 2017
$647k
NCI NIH HHS R01 CA193380NCI NIH HHS R01 CA195500NCI NIH HHS R01 CA239268
6 · The paper itself

Abstract

goalIn this paper, we propose methods for (1) automatic feature extraction and classification for acetic acid and Lugol's iodine cervigrams and (2) methods for combining features/diagnosis of different contrasts in cervigrams for improved performance.

methodsWe developed algorithms to pre-process pathology-labeled cervigrams and extract simple but powerful color and textural-based features. The features were used to train a support vector machine model to classify cervigrams based on corresponding pathology for visual inspection with acetic acid, visual inspection with Lugol's iodine, and a combination of the two contrasts.

resultsThe proposed framework achieved a sensitivity, specificity, and accuracy of 81.3%, 78.6%, and 80.0%, respectively, when used to distinguish cervical intraepithelial neoplasia (CIN+) relative to normal and benign tissues. This is superior to the average values achieved by three expert physicians on the same data set for discriminating normal/benign cases from CIN+ (77% sensitivity, 51% specificity, and 63% accuracy).

conclusionThe results suggest that utilizing simple color- and textural-based features from visual inspection with acetic acid and visual inspection with Lugol's iodine images may provide unbiased automation of cervigrams. SIGNIFICANCE: This would enable automated, expert-level diagnosis of cervical pre-cancer at the point of care.

Indexed as

AlgorithmsColposcopesCervix UteriEarly Detection of CancerFemaleHumansImage Interpretation, Computer-AssistedMachine LearningPoint-of-Care SystemsPrecancerous ConditionsUterine Cervical Neoplasms

Identifiers

PMID30575526
PMCPMC6581620
OpenAlexW2953197682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.