Evidence map›Paper›PMID 30575329›Full record

ArticleCancer medicine2019

Lung cancer costs by treatment strategy and phase of care among patients enrolled in Medicare.

Deirdre F Sheehan, Steven D Criss, Yufan Chen, Andrew Eckel, Lauren Palazzo, Angela C Tramontano, Chin Hur, Lauren E Cipriano, Chung Yin Kong

Abstract read
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

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  19. Estimating surgery, radiotherapy and systemic anti-cancer therapy treatment costs for cancer patients by stage at diagnosis.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deirdre F SheehanInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.
Steven D CrissInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-9394-1381
Yufan ChenInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.
Andrew EckelInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.
Lauren PalazzoInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.
Angela C TramontanoInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0001-5718-6297
Chin HurInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.
Lauren E CiprianoIvey Business School, Western University, London, Ontario, Canada.ORCID 0000-0001-5568-4516
Chung Yin KongInstitute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0001-6431-7830

Funding

Comparative Modeling of Lung Cancer Prevention and Control PoliciesU01CA199284 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DE KONING, HARRY J, HOLFORD, THEODORE R · 2015 to 2019
$8.4M
NCI NIH HHS U01 CA199284
6 · The paper itself

Abstract

backgroundWe studied trends in lung cancer treatment cost over time by phase of care, treatment strategy, age, stage at diagnosis, and histology.

methodsUsing the Surveillance, Epidemiology, and End Results (SEER)-Medicare database for years 1998-2013, we allocated total and patient-liability costs into the following phases of care for 145 988 lung cancer patients: prediagnosis, staging, surgery, initial, continuing, and terminal. Patients served as self-controls to determine cancer-attributable costs based on individual precancer diagnosis healthcare costs. We fit linear regression models to determine cost by age and calendar year for each stage at diagnosis, histology, and treatment strategy and presented all costs in 2017 US dollars.

resultsMonthly healthcare costs prior to lung cancer diagnosis were $861 for a 70 years old in 2017 and rose by an average of $17 per year (P < 0.001). Surgery in 2017 cost $30 096, decreasing by $257 per year (P = 0.007). Chemotherapy and radiation costs remained stable or increased for most stage and histology groups, ranging from $4242 to $8287 per month during the initial six months of care. Costs during the final six months of life decreased for those who died of lung cancer or other causes.

conclusionsCost-effectiveness analyses of lung cancer control interventions in the United States have been using outdated and incomplete treatment cost estimates. Our cost estimates enable updated cost-effectiveness analyses to determine the benefit of lung cancer control from a health economics point of view.

Indexed as

AgedAged, 80 and overFemaleHealth Care CostsHumansLung NeoplasmsMaleMedicareNeoplasm StagingSEER ProgramUnited Stateshealthcare costslung cancerphase of careSEER-Medicaretreatment

Identifiers

PMID30575329
PMCPMC6346221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.