ArticleHuman brain mapping2019
fMRI evidence of aberrant neural adaptation for objects in schizophrenia and bipolar disorder.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Altered temporal dynamics of prefrontal ERP responses reflecting neural adaptation in patients with amnestic mild cognitive impairment.Alzheimer's research & therapy · 2026Article
- Stronger tilt aftereffects in individuals diagnosed with schizophrenia spectrum disorders but not bipolar disorder.Schizophrenia research · 2024Article
- Selective and Systems-Level Face Processing Impairments in ASD.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Habituation, Adaptation and Prediction Processes in Neurodevelopmental Disorders: A Comprehensive Review.Brain sciences · 2023Review
- Diminished Repetition Suppression Reveals Selective and Systems-Level Face Processing Differences in ASD.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Differences of resting fMRI and cognitive function between drug-naïve bipolar disorder and schizophrenia.BMC psychiatry · 2022Article
- Improved correspondence of fMRI visual field localizer data after cortex-based macroanatomical alignment.Scientific reports · 2022Article
- Cortical activation abnormalities in bipolar and schizophrenia patients in a combined oddball-incongruence paradigm.European archives of psychiatry and clinical neuroscience · 2021Article
- Explaining Orientation Adaptation in V1 by Updating the State of a Spatial Model.Frontiers in computational neuroscience · 2021Article
- Pareidolia in Schizophrenia and Bipolar Disorder.Frontiers in psychiatry · 2021Article
- A MEG Study of Visual Repetition Priming in Schizophrenia: Evidence for Impaired High-Frequency Oscillations and Event-Related Fields in Thalamo-Occipital Cortices.Frontiers in psychiatry · 2020Article
- Structural and Functional Connectivity of Visual Cortex in Schizophrenia and Bipolar Disorder: A Graph-Theoretic Analysis.Schizophrenia bulletin open · 2020Article
- Linking resting-state networks and social cognition in schizophrenia and bipolar disorder.Human brain mapping · 2019Article
- fMRI evidence of aberrant neural adaptation for objects in schizophrenia and bipolar disorder.Human brain mapping · 2019Article
- Evidence for intact stimulus-specific neural adaptation for visual objects in schizophrenia and bipolar disorder: An ERP study.PloS one · 2019Observational
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Authors and funding
9 authors.
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Abstract
Functional magnetic resonance imaging (fMRI) adaptation (also known as fMRI repetition suppression) has been widely used to characterize stimulus selectivity in vivo, a fundamental feature of neuronal processing in the brain. We investigated whether SZ patients and BD patients show aberrant fMRI adaptation for object perception. About 52 SZ patients, 55 BD patients, and 53 community controls completed an object discrimination task with three conditions: the same object presented twice, two exemplars from the same category, and two exemplars from different categories. We also administered two functional localizer tasks. A region of interest analysis was employed to evaluate a priori hypotheses about the lateral occipital complex (LOC) and early visual cortex (EVC). An exploratory whole brain analysis was also conducted. In the LOC and EVC, controls showed the expected reduced fMRI responses to repeated presentation of the same objects compared with different objects (i.e., fMRI adaptation for objects, p < .001). SZ patients showed an adaptation effect that was significantly smaller compared with controls. BD patients showed a lack of fMRI adaptation. The whole brain analyses showed enhanced fMRI responses to repeated presentation of the same objects only in BD patients in several brain regions including anterior cingulate cortex. This study was the first to employ fMRI adaptation for objects in SZ and BD. The current findings provide empirical evidence of aberrant fMRI adaptation in the visual cortex in SZ and BD, but in distinctly different ways.
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