ArticleNMR in biomedicine2019
Quantifying cardiac-induced brain tissue expansion using DENSE.
Article in NMR in biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnetic resonance imaging of the pulsing brain: a systematic review.Magma (New York, N.Y.) · 2023Pooled it
- Modelling Motion-Induced Signal Corruption in Steady-State Diffusion MRI.Magnetic resonance in medicine · 2026Article
- Effects and Correction of Patient Bulk Motion in Cranial DENSE MRI.Magnetic resonance in medicine · 2026Article
- Exploring the Role of Vascular Factors and Tissue Properties in Pulsatile Brain Deformation.NMR in biomedicine · 2026Article
- Brain Pulsation Imaging Using Non-Balanced Steady-State Free Precession With 3D-EPI Readout.Magnetic resonance in medicine · 2026Article
- Measuring CSF net velocity in the human subarachnoid space with 7T MRI: testing the classical view of CSF absorption.Fluids and barriers of the CNS · 2025Article
- Measurement of CSF flow and brain motion in Chiari malformation type I subjects undergoing posterior fossa decompression surgery.Journal of neurosurgery · 2025Article
- The pulsing brain: state of the art and an interdisciplinary perspective.Interface focus · 2025Review
- Feasibility of single-shot multi-slice DENSE MRI at 7 T for strain tensor imaging in a paediatric population.Interface focus · 2025Article
- Assessing the feasibility of a new approach to measure the full spectrum of cerebrospinal fluid dynamics within the human brain using MRI: insights from a simulation study.Interface focus · 2025Article
- Article
- The heartbeat induces local volumetric compression in the healthy human brain: a 7 T magnetic resonance imaging study on brain tissue pulsations.Interface focus · 2024Article
- 3D Quantitative-Amplified Magnetic Resonance Imaging (3D q-aMRI).Bioengineering (Basel, Switzerland) · 2024Article
- The Networking Brain: How Extracellular Matrix, Cellular Networks, and Vasculature Shape the In Vivo Mechanical Properties of the Brain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Accelerated multislice MRI with patterned excitation.Magnetic resonance in medicine · 2024Article
- Computational Fluid Dynamics of Cerebrospinal Fluid.Advances in experimental medicine and biology · 2024Review
- Estimating the viscoelastic properties of the human brain at 7 T MRI using intrinsic MRE and nonlinear inversion.Human brain mapping · 2023Article
- Association between resistance to cerebrospinal fluid flow and cardiac-induced brain tissue motion for Chiari malformation type I.Neuroradiology · 2023Article
- The Relationship Between Imbalance Symptom and Cardiac Pulsation Induced Mechanical Strain in the Brainstem and Cerebellum for Chiari Malformation Type I.Journal of biomechanical engineering · 2023Article
- Stiffness pulsation of the human brain detected by non-invasive time-harmonic elastography.Frontiers in bioengineering and biotechnology · 2023Article
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5 authors.
Funding
Abstract
Brain tissue undergoes viscoelastic deformation and volumetric strain as it expands over the cardiac cycle due to blood volume changes within the underlying microvasculature. Volumetric strain measurements may therefore provide insights into small vessel function and tissue viscoelastic properties. Displacement encoding via stimulated echoes (DENSE) is an MRI technique that can quantify the submillimetre displacements associated with brain tissue motion. Despite previous studies reporting brain tissue displacements using DENSE and other MRI techniques, a complete picture of brain tissue volumetric strain over the cardiac cycle has not yet been obtained. To address this need we implemented 3D cine-DENSE at 7 T and 3 T to investigate the feasibility of measuring cardiac-induced volumetric strain as a marker for small vessel blood volume changes. Volumetric strain over the entire cardiac cycle was computed for the whole brain and for grey and white matter tissue separately in six healthy human subjects. Signal-to-noise ratio (SNR) measurements were used to determine the voxel-wise volumetric strain noise. Mean peak whole brain volumetric strain at 7 T (mean ± SD) was (4.5 ± 1.0) × 10
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