Evidence map›Paper›PMID 30574896›Full record

ArticleIndian journal of ophthalmology2019

Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis.

Jitender Jinagal, Gaurav Gupta, Aniruddha Agarwal, Kanika Aggarwal, Madhuri Akella, Vishali Gupta, Deepti Suri, Anju Gupta, Surjit Singh, Jagat Ram

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04333069 (Outcome of Cataract Surgery in Patient With Uveitis), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04333069 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Outcome of Cataract Surgery in Patient With Uveitis

TypeinterventionalSponsorAssiut UniversityRan2020 to 2022Enrolled50ConditionsCataract, ComplicataArmscataract surgery
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jitender JinagalAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Gaurav GuptaAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Aniruddha AgarwalAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Kanika AggarwalAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Madhuri AkellaAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Vishali GuptaAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Deepti SuriDepartment of Pediatrics, Division of Allergy and Immunology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Anju GuptaDepartment of Pediatrics, Division of Allergy and Immunology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Surjit SinghDepartment of Pediatrics, Division of Allergy and Immunology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Jagat RamAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the safety and efficacy of intraoperative intravitreal dexamethasone implant in patients of juvenile idiopathic arthritis (JIA)-associated uveitis undergoing phacoemulsification with posterior chamber intraocular lens (PCIOL) implantation.

methodsRetrospectively, data of patients with JIA-associated uveitis undergoing phacoemulsification with PCIOL implantation with intraoperative dexamethasone implant injection were analyzed. Patients with a minimum follow-up of 6 months were included. Primary outcome measures were ocular inflammation, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and worsening of uveitis.

results8 eyes of 6 patients were included. BCVA was significantly improved at 1, 3, and 6 months postoperatively 0.20 ± 0.09, P = 0.008; 0.18 ± 0.11, P = 0.008; and 0.24 ± 0.11, P = 0.01, respectively. No statistical difference noted in mean IOP at various follow-up visits. None developed worsening of uveitis or Cystoid macular edema.

conclusionIntraoperative intravitreal dexamethasone implant is a safe and effective in preventing and managing the postoperative inflammation in children with JIA-associated uveitic cataract.

Indexed as

Visual AcuityArthritis, JuvenileCataractChildDexamethasoneDrug ImplantsFemaleFollow-Up StudiesGlucocorticoidsHumansIntraocular PressureIntraoperative PeriodIntravitreal InjectionsLens Implantation, IntraocularMalePhacoemulsificationDexamethasoneDrug ImplantsGlucocorticoidscataract surgeryChildrendexamethasone implantJIAjuvenile idiopathic arthritisphacoemulsificationuveitis

Identifiers

PMID30574896
PMCPMC6324120
OpenAlexW2906223086

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.