Evidence map›Paper›PMID 30574893›Full record

ArticleIndian journal of ophthalmology2019

The novel model: Experimental optical coherence tomography-guided anterior segment imaging chick embryo model.

Resat Duman, Tolga Ertekin, Rahmi Duman, Esra Aslan, Mehmet Cem Sabaner, Ersan Cetinkaya

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Resat DumanDepartment of Ophthalmology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Tolga ErtekinDepartment of Anatomy, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Rahmi DumanDepartment of Ophthalmology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Esra AslanDepartment of Histology-Embryology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Mehmet Cem SabanerDepartment of Ophthalmology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Ersan CetinkayaDepartment of Ophthalmology, Antalya Education and Research Hospital, Antalya, Turkey.
Afyon Kocatepe University · TRAntalya Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to present an experimental optical coherence tomography (OCT)-guided anterior segment (AS) imaging chick embryo model. Through this model, we aimed to reveal similarities and differences between human cornea, AS tissues, and chick embryo tissues by quantitative image analysis.

methodsEx vivo, the chick embryos' globes were determined by detailed AS camera of spectral-domain (SD)-OCT in 10 fertilized specific pathogen-free eggs on the 20

resultsSD-OCT imaging was able to successfully delineate the AS tissues of chick embryos such as the cornea, iris, lens, pupil, conjunctiva, ciliary body, anterior chamber, and lens. Quantitative semi-automated measurements showed the following: mean central corneal thickness: 213.4 ± 7.05 μm (197-223 μm), mean anterior chamber depth: 878.9 ± 41.74 (804-919 μm), mean anterior chamber area: 2.43 ± 0.16 mm

conclusionIn conclusion, this chick embryo model mimics human tissues and it can be considered as a platform for the study of teratogen-induced malformations and AS dysgenesis during gestation of AS tissues. In addition, this study demonstrates the feasibility of SD-OCT in the quantitative assessment of AS structures in chick embryo model.

Indexed as

AnimalsAnterior Eye SegmentBiometryChick EmbryoFeasibility StudiesModels, AnimalTomography, Optical CoherenceAnterior segmentchick embryocorneaexperimental animal modelspectral-domain optical coherence tomography

Identifiers

PMID30574893
PMCPMC6324092
OpenAlexW2905854313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.