Evidence map›Paper›PMID 30574870›Full record

ArticleeLife2018

Why we need to report more than 'Data were Analyzed by t-tests or ANOVA'.

Tracey L Weissgerber, Oscar Garcia-Valencia, Vesna D Garovic, Natasa M Milic, Stacey J Winham

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Microglial P2Y12 mediates chronic stress-induced synapse loss in the prefrontal cortex and associated behavioral consequences.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
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  12. How to write statistical analysis section in medical research.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022
    Article
  13. The efficacy of peritonsillar injection of bupivacaine vs intravenous acetaminophen on post-tonsillectomy pain in children.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
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  20. Is the future of peer review automated?BMC research notes · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tracey L WeissgerberDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, United States.ORCID 0000-0002-7490-2600
Oscar Garcia-ValenciaDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, United States.ORCID 0000-0003-0186-9448
Vesna D GarovicDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, United States.ORCID 0000-0001-6891-0578
Natasa M Milic *Division of Nephrology and Hypertension, Mayo Clinic, Rochester, United States.
Stacey J Winham *Division of Biomedical Statistics & Informatics, Mayo Clinic, Rochester, United States.ORCID 0000-0002-8492-9102

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
The role of X chromosome inactivation in ovarian cancerR03CA212127 · NCI · MAYO CLINIC ROCHESTER · PI WINHAM, STACEY J · 2017 to 2018
$159k
NCATS NIH HHS UL1 TR000135NCI NIH HHS R03 CA212127NCI NIH HHS R03-CA212127
6 · The paper itself

Abstract

Transparent reporting is essential for the critical evaluation of studies. However, the reporting of statistical methods for studies in the biomedical sciences is often limited. This systematic review examines the quality of reporting for two statistical tests, t-tests and ANOVA, for papers published in a selection of physiology journals in June 2017. Of the 328 original research articles examined, 277 (84.5%) included an ANOVA or t-test or both. However, papers in our sample were routinely missing essential information about both types of tests: 213 papers (95% of the papers that used ANOVA) did not contain the information needed to determine what type of ANOVA was performed, and 26.7% of papers did not specify what post-hoc test was performed. Most papers also omitted the information needed to verify ANOVA results. Essential information about t-tests was also missing in many papers. We conclude by discussing measures that could be taken to improve the quality of reporting.

Indexed as

Analysis of VarianceHumansResearchResearch DesignResearch ReportStatistics as Topicanalysis of variancehuman biologymedicinemeta-researchnonestatisticssystematic reviewtransparencyt-test

Identifiers

PMID30574870
PMCPMC6326723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.