Evidence map›Paper›PMID 30574806›Full record

ArticleCell transplantation2019

MRI Tracking of iPS Cells-Induced Neural Stem Cells in Traumatic Brain Injury Rats.

Lili Jiang, Ronggang Li, Hailiang Tang, Junjie Zhong, Huaping Sun, Weijun Tang, Huijuan Wang, Jianhong Zhu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lili Jiang1 Department of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Ronggang Li2 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Hailiang Tang2 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Junjie Zhong2 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Huaping Sun3 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Weijun Tang3 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Huijuan Wang1 Department of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Jianhong Zhu2 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Huashan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induced pluripotent stem cells (iPS cells) are promising cell source for stem cell replacement strategy applied to brain injury caused by traumatic brain injury (TBI) or stroke. Neural stem cell (NSCs) derived from iPS cells could aid the reconstruction of brain tissue and the restoration of brain function. However, tracing the fate of iPS cells in the host brain is still a challenge. In our study, iPS cells were derived from skin fibroblasts using the four classic factors Oct4, Sox2, Myc, and Klf4. These iPS cells were then induced to differentiate into NSCs, which were incubated with superparamagnetic iron oxides (SPIOs) in vitro. Next, 30 TBI rat models were prepared and divided into three groups (

Indexed as

AnimalsBrain Injuries, TraumaticCells, CulturedCell TrackingInduced Pluripotent Stem CellsKruppel-Like Factor 4Magnetic Resonance ImagingNeural Stem CellsNeurogenesisRatsRats, Sprague-DawleyKruppel-Like Factor 4induced pluripotent stem cellsmanganese-enhanced MRIneural stem cellssuperparamagnetic iron oxide particlestraumatic brain injury

Identifiers

PMID30574806
PMCPMC6686439
OpenAlexW2906083052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.