ReviewJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2018
Abdominal Sepsis: An Update.
Review in Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06901544 (Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between systemic lupus erythematosus and disruption of gut microbiota: a meta-analysis.Lupus science & medicine · 2022Pooled it
- Clinical evaluation of laparoscopic repair with quadruple therapy for acute gastric ulcer perforation in elderly patients.Frontiers in pharmacology · 2026Article
- Intraoperative Low-Dose Glucocorticoids in Surgical Patients With Abdominal Sepsis: A Multicenter Retrospective Cohort Study.Health science reports · 2025Article
- Multiplexed longitudinal analysis of the cellular and microbial dynamics of acute polymicrobial sepsis in mice.Frontiers in immunology · 2025Article
- Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Article
- Article
- Diagnostic utility of IL-18 plasma levels in distinguishing abdominal from non-abdominal sepsis.Frontiers in immunology · 2025Article
- Microbiological profiles and clinical outcomes of critically ill surgical patients with lower gastrointestinal perforation in Japan: a single-center retrospective observational study.BMC anesthesiology · 2024Observational
- Article
- Source Control and Antibiotics in Intra-Abdominal Infections.Antibiotics (Basel, Switzerland) · 2024Review
- Association between quality control and outcomes of septic shock caused by intestinal perforation in China: a cross-sectional study.Scientific reports · 2023Observational
- Binge-eating and sodium bicarbonate: a potent combination for gastric rupture in adults-two case reports and a review of literature.Journal of eating disorders · 2022Article
- Self-perceived recovery and quality of life in elderly patients surviving ICU-admission for abdominal sepsis.Journal of intensive care medicine · 2022Article
- Functional Characterization of Neutrophils Allows Source Control Evaluation in a Murine Sepsis Model.The Journal of surgical research · 2022Article
- Efficacy ofFrontiers in cellular and infection microbiology · 2022Article
- Mortality audit in general surgery unit and lessons learned at a Nigerian tertiary hospital: a single centre observational study.The Pan African medical journal · 2022Observational
- Article
- Topical Neck Cooling Prolongs Survival of Rats with Intra-Abdominal Feculent Sepsis by Activation of the Vagus Nerve.International journal of molecular sciences · 2021Article
- Predictive value of immune cell counts and neutrophil-to-lymphocyte ratio for 28-day mortality in patients with sepsis caused by intra-abdominal infection.Burns & trauma · 2021Article
- Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.Theranostics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the significant development and advancement in antibiotic therapy, life-threatening complication of infective diseases cause hundreds of thousands of deaths world. This paper updates some of the issues regarding the etiology and treatment of abdominal sepsis and summaries the latest guidelines as recommended by the Intra-abdominal Infection (IAI) Consensus (2017). Prognostic scores are currently used to assess the course of peritonitis. Irrespective of the initial cause, there are several measures universally accepted as contributing to an improved survival rate, with the early recognition of IAI being the critical matter in this respect. Immediate correction of fluid balance should be undertaken with the use of vasoactive agents being prescribed, if necessary, to augment and assist fluid resuscitation. The WISS study showed that mortality was significantly affected by sepsis irrespective of any medical and surgical measures. A significant issue is the prevalence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in the clinical setting, and the reported prevalence of ESBLs intra-abdominal infections has steadily increased in Asia. Europe, Latin America, Middle East, North America, and South Pacific. Abdominal cavity pathology is second only to sepsis occurring in a pulmonary site. Following IAI (2017) guidelines, antibiotic therapy should be initiated as soon as possible after a diagnosis has been verified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.