ArticleEuropean thyroid journal2018
Association between Thyroid-Stimulating Hormone Levels and Non-Alcoholic Fatty Liver Disease Is Not Independent from Metabolic Syndrome Criteria.
Article in European thyroid journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Evidence on the link between hypothyroidism and non-alcoholic fatty liver disease: an updated systematic review.BMC endocrine disorders · 2025Pooled it
- Global epidemiology of type 2 diabetes in patients with NAFLD or MAFLD: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Associations between thyroid axis changes and glycemic improvement after weight loss in type 2 diabetes: a mediation analysis.American journal of translational research · 2026Article
- Prevalence and Associated Factors of Non-Alcoholic Fatty Liver Disease in People Living with HIV-1.Current HIV research · 2025Article
- Thyroid dysfunction in non-alcoholic fatty liver disease: A case-control study.Bioinformation · 2025Article
- Article
- Association between non-alcoholic fatty liver disease and subclinical hypothyroidism in children with obesity.Journal of endocrinological investigation · 2023Article
- Article
- Low-Normal Thyroid Function Is Not Associated with Either Non-Alcoholic Fatty Liver Disease or with Metabolic Dysfunction-Associated Fatty Liver Disease.Life (Basel, Switzerland) · 2023Article
- Association of Thyroid Hormone Treatment Intensity With Cardiovascular Mortality Among US Veterans.JAMA network open · 2022Article
- Central Obesity Is Associated with Variations in TSH and ACTH Levels among Euthyroid Obese Individuals.International journal of endocrinology · 2022Article
- Fish and the Thyroid: A Janus Bifrons Relationship Caused by Pollutants and the Omega-3 Polyunsaturated Fatty Acids.Frontiers in endocrinology · 2022Review
- Abnormal transaminase and lipid profiles in coexisting diseases in patients with fatty liver: a population study in Sichuan.Bioscience reports · 2021Article
- Evaluation of thyroid function and thyroid autoimmune disease in patients with non-alcoholic fatty liver disease.Clinical and experimental hepatology · 2021Article
- TSH Levels as an Independent Risk Factor for NAFLD and Liver Fibrosis in the General Population.Journal of clinical medicine · 2021Article
- Review
- The Role of Thyroid Hormones and Autoantibodies in Metabolic Dysfunction Associated Fatty Liver Disease: TgAb May Be a Potential Protective Factor.Frontiers in endocrinology · 2020Article
- THE RELATIONSHIP BETWEEN TSH LEVELS, THYROID AUTOANTIBODIES AND ATHEROGENIC INDEX OF PLASMA, AST TO PLATELET RATIO INDEX SCORE, AND FIBROSIS 4 INDEX IN PATIENTS WITH HYPOTHYROIDISM.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThyroid hormones are involved in the regulation of body composition, lipid metabolism, and insulin resistance. Thus, it is possible that they might play a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the role of thyroid function on NAFLD is not well defined. In this study, we evaluated the relationship between thyroid-stimulating hormone (TSH) levels, within the reference range, and presence of NAFLD in asymptomatic individuals. STUDY
designWe included all individuals evaluated at a preventive clinic of the Hospital Israelita Albert Einstein, between 2014 and 2015. The prevalence of NAFLD (analyzed by abdominal ultrasound), according to TSH quartiles, within the reference range, was determined. The association between TSH quartiles and NAFLD was analyzed by logistic regression adjusted for possible confounders.
resultsWe evaluated 10,539 individuals (73% male, age 43.4 ± 9.4 years). The prevalence of NAFLD was 34, 38, 38, and 39% in the first to the fourth TSH quartiles (0.46-1.44, 1.45-1.97, 1.98-2.68, and 2.69-4.68 mUI/L, respectively,
conclusionsAlthough the TSH variability within the reference range is associated with NAFLD in univariable models, once adjusted for metabolic syndrome factors no significant association is noted.
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