Evidence map›Paper›PMID 30574454›Full record

ArticleFrontiers in oncology2018

The Polycomb BMI1 Protein Is Co-expressed With CD26+ in Leukemic Stem Cells of Chronic Myeloid Leukemia.

Sara Galimberti, Susanna Grassi, Claudia Baratè, Francesca Guerrini, Elena Ciabatti, Francesca Perutelli, Federica Ricci, Giada Del Genio, Marina Montali, Serena Barachini and 15 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01860456 (Tyrosine Kinase Inhibitors of BCR/ABL), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01860456 completednot on this map

Tyrosine Kinase Inhibitors of BCR/ABL: Pharmacokinetic and Pharmacogenetic Study in Patients Affected by Chronic Myeloid Leukemia. Evaluation of Efficacy and Tolerability

TypeobservationalSponsorUniversity of PisaRan2013 to 2024Enrolled412ConditionsChronic Myeloid LeukemiaArmsImatinib/Nilotinib
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Drug resistance and Cancer stem cells.Cell communication and signaling : CCS · 2021
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Strategies For Targeting Chronic Myeloid Leukaemia Stem Cells.Blood and lymphatic cancer : targets and therapy · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 6 institutions in 1 country.

Sara GalimbertiSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Susanna GrassiSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Claudia BaratèSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Francesca GuerriniSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Elena CiabattiSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Francesca PerutelliSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Federica RicciSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Giada Del GenioUnità Operativa Cytogenetics, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Marina MontaliSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Serena BarachiniSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Cecilia GiulianiUnità Operativa Cytogenetics, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Maria Immacolata FerreriUnità Operativa Cytogenetics, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Angelo ValettoUnità Operativa Cytogenetics, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Elisabetta AbruzzeseUnità Operativa Ematologia, Ospedale S. Eugenio, Rome, Italy.
Chiara IppolitoSection of Histology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Alessandra IurloHematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Monica BocchiaUnità Operativa Ematologia, Università di Siena, Siena, Italy.
Anna SicuranzaUnità Operativa Ematologia, Università di Siena, Siena, Italy.
Bruno MartinoUnità Operativa Ematologia, Ospedale Binco, Melacrino, Morelli, Reggio Calabria, Italy.
Lorenzo IovinoSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Gabriele BudaSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Serena SalehzadehSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Mario PetriniSection of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Antonello Di PaoloSection of Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Letizia MattiiSection of Histology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
University of Pisa · ITAzienda Ospedaliera Universitaria Pisana · ITUniversity of Siena · ITAzienda ospedaliera "Bianchi-Melacrino-Morelli" · ITOspedale Maggiore · ITSt. Eugenio Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Polycomb gene

Indexed as

BCR-ABL1BMI1CD26CMLleukemic stem cellpolycomb

Identifiers

PMID30574454
PMCPMC6291509
OpenAlexW2904712747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.