Evidence map›Paper›PMID 30574321›Full record

ArticleUnited European gastroenterology journal2018

Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation-wide multicentre study.

Robert A Moran, Guillermo García-Rayado, Daniel de la Iglesia-García, Emma Martínez-Moneo, Esther Fort-Martorell, Eugenia Lauret-Braña, Mar Concepción-Martín, Fabio Ausania, Carlos Prieto-Martínez, Miguel González-de-Cabo and 19 more

Open access · greenAbstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 20 institutions in 2 countries.

Robert A MoranDivision of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, USA.
Guillermo García-RayadoDepartment of Gastroenterology, Aragón Health Research Institute (IIS Aragón), Zaragoza, Spain.
Daniel de la Iglesia-GarcíaDepartment of Gastroenterology, Complejo Hospitalario de Santiago, Santiago, Spain.
Emma Martínez-MoneoDepartment of Gastroenterology, Hospial Universitario Cruces, Barakaldo, Spain.
Esther Fort-MartorellDepartment of Gastroenterology, Hospital Universitari de Girona Doctor Josep Trueta, Girona, Spain.
Eugenia Lauret-BrañaDepartment of Gastroenterology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Mar Concepción-MartínDepartment of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Fabio AusaniaDepartment of Surgery, Hospital Xeral, Vigo, Spain.
Carlos Prieto-MartínezDepartment of Gastroenterology, Complejo Universitario de Navarra, Pamplona, Spain.
Miguel González-de-CaboDepartment of Radiology, Hospital Son Llatzer, Palma de Mallorca, Spain.
Noé Quesada-VázquezDepartment of Gastroenterology, Hospital General Universitario de Alicante, Alicante, Spain.
M Asunción Marcaide-Ruiz-de-ApodacaDepartment of Gastroenterology, Hospital Universitario Araba, Vitoria-Gasteiz, Spain.
José A Pajares-DíazDepartment of Gastroenterology, Hospital Gregorio Marañón, Madrid, Spain.
Francia C DíazDepartment of Gastroenterology, Hospital Universitari i Politècnic la Fe, Valencia, Spain.
José L de-BenitoDepartment of Radiology, Hospital Clínico de Zaragoza, Zaragoza, Spain.
Jennifer Hinojosa-GuadixDepartment of Gastroenterology, Hospital Costa del Sol, Marbella, Spain.
Pilar Marqués-GarcíaDepartment of Gastroenterology, Hospital Arnau de Vilanova, Valencia, Spain.
Jaume BoadasDepartment of Gastroenterology, Consorci Sanitari Terrassa, Barcelona, Spain.
Eduardo Bajador-AndreuDepartment of Gastroenterology, Hospital Universitario Miguel Servet, Zaragoza, Spain.ORCID https://orcid.org/0000-0002-1732-2941
Oswaldo MorenoDepartment of Gastroenterology, Hospital Clínico, Valencia, Spain.
Federico Argüelles-AriasDepartment of Gastroenterology, Hospital Universitario Vírgen Macarena, Sevilla, Spain.
Gregorio Martín-BenítezDepartment of Radiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Carla Tafur-SánchezDepartment of Gastroenterology, Hospital Clínico Universitario, Valladolid, Spain.
Jesús Leal-TéllezDepartment of Radiology, Hospital Puerta del Mar, Cádiz, Spain.
Beatriz Romero-MosqueraDepartment of Gastroenterology, Hospital Meixoeiro, Vigo, Spain.
Ruben HernaezDepartment of Gastroenterology, Baylor College of Medicine, Houston, USA.
Georgios I PapachristouDivision of Gastroenterology, University of Pittsburgh Medical Center, Pittsburgh, USA.
Vikesh K SinghDivision of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, USA.
Enrique de-MadariaDepartment of Gastroenterology, Hospital General Universitario de Alicante, Alicante, Spain.ORCID https://orcid.org/0000-0002-2412-9541
Hospital General Universitario de Alicante Doctor Balmis · ESJohns Hopkins University · USBaylor College of Medicine · USComplejo Hospitalario de Navarra · ESComplejo Hospitalario Universitario de Santiago · ESConsorci Sanitari de Terrassa · ESHealth First · USHospital Arnau de Vilanova · ESHospital Clínico Universitario de Valencia · ESHospital Clínico Universitario de Valladolid · ESHospital Clínico Universitario Lozano Blesa · ESHospital Costa del Sol · ESHospital de Cruces · ESHospital de Sant Pau · ESHospital General Universitario Gregorio Marañón · ESHospital Son Llatzer · ESHospital Universitari de Girona Doctor Josep Trueta · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario Araba · ESHospital Universitario Central de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are few large prospective cohort studies evaluating predictors of outcomes in acute pancreatitis.

objectivesThe purpose of this study was to determine the role of age and co-morbid disease in predicting major outcomes in acute pancreatitis.

methodsData points were collected according to a predefined electronic data collection form. Acute pancreatitis and its complications were defined according to the revised Atlanta classification. Univariable and multivariable analyses were conducted using Cox proportional hazard regression and multiple logistic regression.

resultsFrom June 2013-February 2015, 1655 adult patients were recruited from 23 centres across Spain. Co-morbid disease, obesity, open surgical necrosectomy within 30 days, and pancreatic necrosis were independently associated with both 30-day mortality and persistent organ failure (

conclusionComorbidity and obesity are important determinates of mortality and persistent organ failure in acute pancreatitis, but in the absence of organ failure they do not appear to independently contribute to morbidity. This has important implications for severity classification and predictive models of severity in acute pancreatitis.

Indexed as

Acute pancreatitiscomorbiditiescomorbiditymorbiditymortalityorgan failure

Identifiers

PMID30574321
PMCPMC6297924
OpenAlexW2891984900

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.