Evidence map›Paper›PMID 30574213›Full record

ArticleMobile DNA2018

Carbapenemases on the move: it's good to be on ICEs.

João Botelho, Adam P Roberts, Ricardo León-Sampedro, Filipa Grosso, Luísa Peixe

Open access · goldAbstract read
In one paragraph

Article in Mobile DNA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Nationwide genome surveillance of carbapenem-resistantAntimicrobial agents and chemotherapy · 2024
    Article
  8. Novel resistance ICEs carrying theAntimicrobial agents and chemotherapy · 2024
    Article
  9. Genetic Characteristics of Novel IncInfection and drug resistance · 2024
    Article
  10. Coexistence ofFrontiers in cellular and infection microbiology · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. β-lactam Resistance inPathogens (Basel, Switzerland) · 2021
    Review
  15. The prevalence and functional characteristics of CrpP-like in Pseudomonas aeruginosa isolates from China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  16. Article
  17. Isolation Procedure for CPMicroorganisms · 2021
    Article
  18. Article
  19. Review
  20. Co-harboring of NovelFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

João Botelho1UCIBIO/REQUIMTE, Laboratório de Microbiologia, Faculdade de Farmácia da Universidade do Porto, Rua Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.ORCID 0000-0002-2771-2345
Adam P Roberts2Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK.
Ricardo León-Sampedro4Department of Microbiology, University Hospital Ramón y Cajal, Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain.
Filipa Grosso1UCIBIO/REQUIMTE, Laboratório de Microbiologia, Faculdade de Farmácia da Universidade do Porto, Rua Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.
Luísa Peixe1UCIBIO/REQUIMTE, Laboratório de Microbiologia, Faculdade de Farmácia da Universidade do Porto, Rua Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.
Universidade do Porto · PTInstituto Cajal · ESLiverpool School of Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe evolution and spread of antibiotic resistance is often mediated by mobile genetic elements. Integrative and conjugative elements (ICEs) are the most abundant conjugative elements among prokaryotes. However, the contribution of ICEs to horizontal gene transfer of antibiotic resistance has been largely unexplored.

resultsHere we report that ICEs belonging to mating-pair formation (MPF) classes G and T are highly prevalent among the opportunistic pathogen

conclusionsThe data presented here provides a global snapshot of the different CEG-harbouring ICEs and sheds light on the underappreciated contribution of these elements to the evolution and dissemination of antibiotic resistance on

Indexed as

Antibiotic resistanceCarbapenemasesIntegrative and conjugative elementsPseudomonas spp.

Identifiers

PMID30574213
PMCPMC6299553
OpenAlexW2885105282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.