Evidence map›Paper›PMID 30574190›Full record

ArticleTherapeutic advances in gastroenterology2018

Diagnostic accuracy of i-scan image enhancement for real-time endoscopic diagnosis of small colorectal polyps: a meta-analysis.

Ben Glover, Nisha Patel, Hutan Ashrafian, Julian Teare

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Endoscopic and pathological characteristics ofWorld journal of gastroenterology · 2023
    Article
  3. Image enhanced colonoscopy: updates and prospects-a review.Translational gastroenterology and hepatology · 2023
    Review
  4. Article
  5. Article
  6. The evolution of lower gastrointestinal endoscopy: where are we now?Therapeutic advances in gastrointestinal endoscopy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ben GloverImperial College London Department of Surgery and Cancer, St Mary's Hospital, Praed Street, London, SW7 2AZ, UK.ORCID https://orcid.org/0000-0003-3043-0012
Nisha PatelImperial College London Department of Surgery and Cancer, London, UK.
Hutan AshrafianImperial College London Department of Surgery and Cancer, London, UK.
Julian TeareImperial College London Department of Surgery and Cancer, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivei-Scan is a digital image enhancement technology, reported to improve diagnostic performance during endoscopy. Previous studies have investigated the accuracy of i-scan for distinguishing between neoplastic and non-neoplastic colonic polyps and suggested diagnostic accuracy close to that required for use in routine clinical practice. The aim of this study was to perform a meta-analysis of the available literature investigating diagnostic accuracy for i-scan optical diagnosis when made in real time for colorectal polyps <10 mm in size. DATA SOURCES: The databases of

methodsA bivariate random effects model was used to produce pooled sensitivity and specificity values, and univariable meta-regression was applied for subgroup analysis.

resultsThe meta-analysis included 15 studies, and diagnosis of 2817 polyps. The area under the hierarchical summary receiver-operating characteristic curve was 0.96. The pooled sensitivity of i-scan optical diagnosis was 0.92 (95% confidence interval 0.85-0.95). The specificity was 0.90 (95% confidence interval 0.83-0.94).

conclusionsThis meta-analysis updates and summarizes the available evidence concerning the diagnostic performance of i-scan for small colorectal polyps. An acceptable degree of accuracy was found, showing potential to support a 'resect and discard' strategy for colonic polyps. There was not found to be a significant difference in diagnostic performance between different clinical settings (i.e. teaching hospitals or general hospitals).

Indexed as

colonoscopyimage-enhanced endoscopyi-scanoptical biopsypolypvirtual chromendoscopy

Identifiers

PMID30574190
PMCPMC6295743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.