ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2018
Review of cold-induced urticaria characteristics, diagnosis and management in a Western Canadian allergy practice.
Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Cryoglobulins, Cryofibrinogens, and Cold Agglutinins in Cold Urticaria: Literature Review, Retrospective Patient Analysis, and Observational Study in 49 Patients.Frontiers in immunology · 2021Pooled it
- Dupilumab in patients with cold urticaria: Results from a phase 3 trial.The journal of allergy and clinical immunology. Global · 2026Article
- Challenges in Differentiating Chronic Inducible Urticaria from Chronic Spontaneous Urticaria.Journal of inflammation research · 2026Review
- Cold-Induced Symptoms in a Young Female: A Perioperative Case of Cold Urticaria for Gynecologic Surgery-A Case Report.Case reports in anesthesiology · 2026Article
- Scoping review: biomarkers in chronic inducible urticaria.Frontiers in immunology · 2026Article
- Article
- Cold Anaphylaxis in Children: Italian Case Series and Review of the Literature.Diseases (Basel, Switzerland) · 2023Article
- Anaphylaxis Caused by Swimming: A Case Report of Cold-induced Urticaria in the Emergency Department.Clinical practice and cases in emergency medicine · 2021Article
- Prevalence of Chronic Inducible Urticaria in Elderly Patients.Journal of clinical medicine · 2021Article
- Atypical Skin Manifestations During Immune Checkpoint Blockage in Coronavirus Disease 2019-Infected Patients With Lung Cancer.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2020Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCold-induced urticaria is a significant condition, especially among young females. Despite the morbidity of this disease, studies that fully characterize the disease are limited.
methodsWe analyzed the characteristics of patients diagnosed with cold-induced urticaria at a community-based allergy practice in Vancouver, BC, Canada between 2003 and 2016. Detailed patient history, diagnostic measures and treatment were evaluated.
resultsA total of 50 patients were found to have active cold-induced urticaria with a median age of 28.5 (range 2-67) years and 35 patients (70%) were female. 16 patients (32%) had co-occurring physical urticarias while 26 patients (52%) had secondary allergic diagnoses and 3 patients (6%) were thought to have a provoking factor. Of those with a clinical history of suspected cold-induced urticaria that were evaluated with ice cube testing, a positive test was obtained in 84.7% of patients. Treatment was largely with non-sedating antihistamines, with the majority of patients receiving this modality.
conclusionsCold-induced urticaria is a complex disease with significant overlap with other chronic inducible urticarias and other allergic diseases. Diagnostic testing shows inconsistent results and the mainstay of treatment consists of non-sedating antihistamines, with other options available for those who do not respond.
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