ArticleFrontiers in aging neuroscience2018
Amnestic Mild Cognitive Impairment Is Associated With Frequency-Specific Brain Network Alterations in Temporal Poles.
Article in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 37 citations in OpenAlex.
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- Comparison of classification algorithms for predicting autistic spectrum disorder using WEKA modeler.BMC medical informatics and decision making · 2022Article
- Minimum spanning tree analysis of brain networks: A systematic review of network size effects, sensitivity for neuropsychiatric pathology, and disorder specificity.Network neuroscience (Cambridge, Mass.) · 2022Article
- A night of sleep deprivation alters brain connectivity and affects specific executive functions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Topological changes of brain network during mindfulness meditation: an exploratory source level magnetoencephalographic study.AIMS neuroscience · 2022Article
- Distinct Effects of the Apolipoprotein E ε4 Genotype on Associations Between Delayed Recall Performance and Resting-State Electroencephalography Theta Power in Elderly People Without Dementia.Frontiers in aging neuroscience · 2022Article
- Detection of Mild Cognitive Impairment with MEG Functional Connectivity Using Wavelet-Based Neuromarkers.Sensors (Basel, Switzerland) · 2021Article
- Functional brain network topology across the menstrual cycle is estradiol dependent and correlates with individual well-being.Journal of neuroscience research · 2021Article
- Article
- Functional Brain Networks in Mild Cognitive Impairment Based on Resting Electroencephalography Signals.Frontiers in computational neuroscience · 2021Article
- Wide temporal horns are associated with cognitive dysfunction, as well as impaired gait and incontinence.Scientific reports · 2020Article
- Neuronal Avalanches to Study the Coordination of Large-Scale Brain Activity: Application to Rett Syndrome.Frontiers in psychology · 2020Article
- Disrupted Patterns of Rich-Club and Diverse-Club Organizations in Subjective Cognitive Decline and Amnestic Mild Cognitive Impairment.Frontiers in neuroscience · 2020Article
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is general agreement that the neuropathological processes leading to Alzheimer's disease (AD) begin decades before the clinical onset. In order to detect early topological changes, we applied functional connectivity and network analysis to magnetoencephalographic (MEG) data obtained from 16 patients with amnestic Mild Cognitive Impairment (aMCI), a prodromal stage of AD, and 16 matched healthy control (HCs). Significant differences between the two groups were found in the theta band, which is associated with memory processes, in both temporal poles (TPs). In aMCI, the degree and betweenness centrality (BC) were lower in the left superior TP, whereas in the right middle TP the BC was higher. A statistically significant negative linear correlation was found between the BC of the left superior TP and a delayed recall score, a sensitive marker of the "hippocampal memory" deficit in early AD. Our results suggest that the TPs, which are involved early in AD pathology and belong to the memory circuitry, have an altered role in the functional network in aMCI.
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