Evidence map›Paper›PMID 30573679›Full record

ArticleThe Journal of biological chemistry2019

Histone acetyltransferase CBP is critical for conventional effector and memory T-cell differentiation in mice.

Ann R Piccirillo, Richard T Cattley, Louise M D'Cruz, William F Hawse

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Journal of Cancer · 2021
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ann R PiccirilloFrom the Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.ORCID 0000-0001-7464-9222
Richard T CattleyFrom the Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
Louise M D'CruzFrom the Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 ldcruz@pitt.edu.
William F HawseFrom the Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 whawse@pitt.edu.
University of Pittsburgh · US

Funding

Determining the proteomic differences that define CD8+ memory T cell recall responseR21AI135406 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI D'CRUZ, LOUISE M., HAWSE, WILLIAM FRANCIS · 2018 to 2019
$424k
NIAID NIH HHS R21 AI135406
6 · The paper itself

Abstract

Compared with naïve T cells, memory CD8

Indexed as

Immunologic MemoryAcetylationAnimalsCD8-Positive T-LymphocytesCell DifferentiationCREB-Binding ProteinEnzyme ActivationHistonesJanus Kinase 2MiceMice, KnockoutPhosphorylationSignal TransductionCREB-Binding ProteinCrebbp protein, mouseHistonesJak2 protein, mouseJanus Kinase 2acetyllysineadaptive immunitybromo domainCD8+ T cellCREB binding proteincytokinedifferentiationhistoneimmune responseinfectionJak2Janus kinase (JAK)kinase signalingmemory T cellproteomicssignal transductionT-cellT-cell receptor (TCR)

Identifiers

PMID30573679
PMCPMC6378974
OpenAlexW2906086042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.