ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Cross-Modal Competition: The Default Computation for Multisensory Processing.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed.
- Echoes of the mind's eye: Reciprocal crossmodal interaction between auditory and visual processing.iScience · 2026Article
- A neuro-computational framework for modeling the development of cross-sensory interactions in Autism: from mechanistic understanding to targeted intervention.Research square · 2026Article
- Incomplete binaural restoration in single-sided deafness treated with cochlear implants: insights from compensatory head-orienting behaviors.Frontiers in neuroscience · 2026Article
- Is Competition the Default Configuration of Cross-Sensory Interactions?The European journal of neuroscience · 2025Article
- The brain can develop conflicting multisensory principles to guide behavior.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- The Development of Multisensory Integration at the Neuronal Level.Advances in experimental medicine and biology · 2024Article
- Repeated passive visual experience modulates spontaneous and non-familiar stimuli-evoked neural activity.Scientific reports · 2023Article
- Noise-rearing precludes the behavioral benefits of multisensory integration.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Crossmodal interactions in human learning and memory.Frontiers in human neuroscience · 2023Review
- Multisensory integration in humans with spinal cord injury.Scientific reports · 2022Article
- Resolution of impaired multisensory processing in autism and the cost of switching sensory modality.Communications biology · 2022Article
- Audiovisual spatial recalibration but not integration is shaped by early sensory experience.iScience · 2022Article
- Unveiling Dynamic System Strategies for Multisensory Processing: From Neuronal Fixed-Criterion Integration to Population Bayesian Inference.Research (Washington, D.C.) · 2022Article
- Multilevel rhythms in multimodal communication.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Neuroplasticity and Crossmodal Connectivity in the Normal, Healthy Brain.Psychology & neuroscience · 2021Article
- Multisensory enhancement of overt behavior requires multisensory experience.The European journal of neuroscience · 2021Article
- Stimulus value gates multisensory integration.The European journal of neuroscience · 2021Article
- Using superior colliculus principles of multisensory integration to reverse hemianopia.Neuropsychologia · 2020Article
- Experience Creates the Multisensory Transform in the Superior Colliculus.Frontiers in integrative neuroscience · 2020Article
- Primary sensory map formations reflect unique needs and molecular cues specific to each sensory system.F1000Research · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Mature multisensory superior colliculus (SC) neurons integrate information across the senses to enhance their responses to spatiotemporally congruent cross-modal stimuli. The development of this neurotypic feature of SC neurons requires experience with cross-modal cues. In the absence of such experience the response of an SC neuron to congruent cross-modal cues is no more robust than its response to the most effective component cue. This "default" or "naive" state is believed to be one in which cross-modal signals do not interact. The present results challenge this characterization by identifying interactions between visual-auditory signals in male and female cats reared without visual-auditory experience. By manipulating the relative effectiveness of the visual and auditory cross-modal cues that were presented to each of these naive neurons, an active competition between cross-modal signals was revealed. Although contrary to current expectations, this result is explained by a neuro-computational model in which the default interaction is mutual inhibition. These findings suggest that multisensory neurons at all maturational stages are capable of some form of multisensory integration, and use experience with cross-modal stimuli to transition from their initial state of competition to their mature state of cooperation. By doing so, they develop the ability to enhance the physiological salience of cross-modal events thereby increasing their impact on the sensorimotor circuitry of the SC, and the likelihood that biologically significant events will elicit SC-mediated overt behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.