Evidence map›Paper›PMID 30573541›Full record

ArticleBMJ case reports2018

The risky side of weight-loss dietary supplements: disrupting arrhythmias causing sudden cardiac arrest.

Faisal Inayat, Chaudhry Nasir Majeed, Nouman Safdar Ali, Maham Hayat, Izzah Vasim

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Weight Management Treatment Representations: A Novel Use of the Common Sense Model.Journal of clinical psychology in medical settings · 2023
    Article
  5. Weight Loss Supplements.Molecules (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Faisal InayatAllama Iqbal Medical College, Lahore, Pakistan.ORCID http://orcid.org/0000-0001-7576-7319
Chaudhry Nasir MajeedWake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.
Nouman Safdar AliAllama Iqbal Medical College, Lahore, Pakistan.
Maham HayatOklahoma University Medical Center, Oklahoma City, Oklahoma, USA.
Izzah VasimWake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.
Allama Iqbal Medical College · PKAtrium Health Wake Forest Baptist · USUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The worldwide increasing prevalence of obesity has led to a corresponding increase in consumption of weight-loss dietary supplements. The limited de novo regulatory oversight and under-reported toxicity profile of these products reflect as a constellation of newer adverse events. We chronicle here the case of an otherwise healthy woman who developed ventricular fibrillation-related cardiac arrest secondary to the use of Hydroxycut and Metaboost preparations. Published medical literature has a handful of case reports associating these products with potentially life-threatening cardiac arrhythmias. The proposed hypothesis implicates ingredients of these diet aids to have proarrhythmogenic effects. Physicians should remain vigilant for possible cardiotoxicity associated with the use of dietary supplements. Individuals who are at risk of developing cardiac arrhythmias should avoid herbal weight-loss formulas, given the serious clinical implications. Additionally, this paper highlights the need for a proper framework to delineate the magnitude and scope of this association.

Indexed as

Anti-Obesity AgentsDietary SupplementsFemaleHeart-Assist DevicesHumansMiddle AgedOut-of-Hospital Cardiac ArrestPlant PreparationsTachycardia, VentricularAnti-Obesity AgentshydroxycutPlant Preparationsarrhythmiasdrug interactionshealthcare improvement and patient safetyobesity (public health)vitamins and supplements

Identifiers

PMID30573541
PMCPMC6303658
OpenAlexW2905972834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.