Evidence map›Paper›PMID 30573509›Full record

ArticleHaematologica2019

Tspan18 is a novel regulator of the Ca

Peter J Noy, Rebecca L Gavin, Dario Colombo, Elizabeth J Haining, Jasmeet S Reyat, Holly Payne, Ina Thielmann, Adam B Lokman, Georgiana Neag, Jing Yang and 17 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Cracking the Endothelial Calcium (CaInternational journal of molecular sciences · 2023
    Review
  8. Article
  9. The Molecular Heterogeneity of Store-Operated CaInternational journal of molecular sciences · 2023
    Review
  10. Article
  11. Reactive Oxygen Species and Endothelial CaInternational journal of molecular sciences · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Tspan18 is a novel regulator of thrombo-inflammation.Medical microbiology and immunology · 2020
    Review
  16. Tetraspanins in the regulation of mast cell function.Medical microbiology and immunology · 2020
    Review
  17. Review
  18. Review
  19. Endothelial CaInternational journal of molecular sciences · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 6 institutions in 3 countries.

Peter J NoySchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Rebecca L GavinSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Dario ColomboInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Elizabeth J HainingInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Jasmeet S ReyatSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Holly PayneInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Ina ThielmannUniversity Hospital Würzburg and Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany.
Adam B LokmanInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Georgiana NeagInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Jing YangSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Tammy LloydSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Neale HarrisonSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Victoria L HeathInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Chris GardinerDepartment of Haematology, University College London, London, UK.
Katharine M WhitworthInstitute of Immunology and Immunotherapy, Cancer Immunology and Immunotherapy Centre, University of Birmingham, Birmingham, UK.
Joseph RobinsonInstitute of Immunology and Immunotherapy, Cancer Immunology and Immunotherapy Centre, University of Birmingham, Birmingham, UK.
Chek Z KooSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Alessandro Di MaioSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
Paul HarrisonScar Free Foundation for Burns Research, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham National Health Service (NHS) Foundation Trust, Birmingham, UK.
Steven P LeeInstitute of Immunology and Immunotherapy, Cancer Immunology and Immunotherapy Centre, University of Birmingham, Birmingham, UK.
Francesco MichelangeliDepartment of Biological Sciences, University of Chester, Chester, UK.
Neena KaliaInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
G Ed RaingerInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Bernhard NieswandtUniversity Hospital Würzburg and Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany.
Alexander BrillInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Steve P WatsonInstitute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Michael G TomlinsonSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK m.g.tomlinson@bham.ac.uk.
University of Birmingham · GBUniversitätsklinikum Würzburg · DEUniversity College London · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity of Chester · GBUniversity of Nottingham · GB

Funding

British Heart Foundation FS/08/062/25797British Heart Foundation FS/12/79/29871British Heart Foundation FS/14/42/30956British Heart Foundation FS/18/9/33388British Heart Foundation PG/13/92/30587British Heart Foundation RG/12/7/29693Medical Research Council G0400247
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsB-LymphocytesCalciumChickensDisease Models, AnimalGene Expression RegulationHEK293 CellsHeLa CellsHistamineHumansHuman Umbilical Vein Endothelial CellsIon TransportJurkat CellsMiceMice, Inbred C57BLMice, KnockoutCalciumHistamineNFATC Transcription FactorsORAI1 ProteinORAI1 protein, humanTetraspaninsThrombinTSPAN18 protein, humanvon Willebrand Factor

Identifiers

PMID30573509
PMCPMC6717597
OpenAlexW2905770259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.