Evidence map›Paper›PMID 30573501›Full record

ArticleHaematologica2019

Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses.

Rinske van Oorschot, Anna E Marneth, Saskia M Bergevoet, Maaike G J M van Bergen, Kathelijne Peerlinck, Claire E Lentaigne, Carolyn M Millar, Sarah K Westbury, Remi Favier, Wendy N Erber and 8 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 5 countries.

Rinske van OorschotDepartment of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands.
Anna E MarnethDepartment of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands.
Saskia M BergevoetDepartment of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands.
Maaike G J M van BergenDepartment of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands.
Kathelijne PeerlinckDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, Belgium.
Claire E LentaigneCentre for Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, UK.
Carolyn M MillarCentre for Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, UK.
Sarah K WestburySchool of Cellular and Molecular Medicine, University of Bristol, UK.
Remi FavierService d'Hematologie Biologique, Assistance-Publique Hôpitaux de Paris, Centre de Référence des Pathologies Plaquettaires, Hôpital Armand Trousseau, Paris, France.
Wendy N ErberSchool of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.
Ernest TurroDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.
Joop H JansenDepartment of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands.
Willem H OuwehandDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.
Harriet L McKinneyDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.
NIHR BioResource Collaborative Group
Kate DownesDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.
Kathleen FresonDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, Belgium.
Bert A van der ReijdenDepartment of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands Bert.vanderReijden@radboudumc.nl.
Radboud University Nijmegen · NLNational Health Service · GBImperial College Healthcare NHS Trust · GBImperial College London · GBKU Leuven · BESorbonne Université · FRThe University of Western Australia · AUUniversity of Bristol · GB

Funding

Medical Research Council MR/J011711/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease SusceptibilityMutation, MissenseAllelesGene ExpressionGenetic Association StudiesGenotypeHemorrhagic DisordersHumansPedigreeProto-Oncogene ProteinsRepressor ProteinsGFI1B protein, humanProto-Oncogene ProteinsRepressor Proteins

Identifiers

PMID30573501
PMCPMC6545829
OpenAlexW2906223268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.