SynthesisBMJ open2018
Systematic literature review on which maternal alcohol behaviours are related to fetal alcohol spectrum disorders (FASD).
Synthesis in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 48 citations in OpenAlex.
- Subtle Cognitive Variability in Foetal Alcohol Syndrome Spectrum: Intelligence Profiles and Verbal Fluency Performance Across Diagnostic Categories in Polish Population.Journal of clinical medicine · 2026Article
- Lifestyle Management for Pregnant Women with Polyendocrine Metabolic Ovarian Syndrome Based on Integrated Traditional Chinese and Western Medicine: A Group Consensus.Journal of multidisciplinary healthcare · 2026Article
- Does paternal alcohol consumption affect the severity of traits of fetal alcohol spectrum disorders?Alcohol, clinical & experimental research · 2025Article
- Clinical Features of Typically Developing Children with and without Prenatal Alcohol Exposure.The Journal of pediatrics · 2025Article
- Differentiating Fetal Alcohol Spectrum Disorder from other neurodevelopmental disorders: neurocognitive and socio-emotional evidence.Frontiers in neuroscience · 2025Article
- Maternal and paternal risk factors associated with diagnoses within the continuum of fetal alcohol spectrum disorders in the USA: Proximal and distal influences.Alcohol, clinical & experimental research · 2025Article
- Influence of childhood trauma and traumatic stress on a woman's risk of having a child with a fetal alcohol spectrum disorder.Alcohol, clinical & experimental research · 2024Article
- The association between depression and alcohol use among pregnant adults in the USA.Archives of women's mental health · 2024Article
- Low to moderate prenatal alcohol exposure and neurodevelopment in a prospective cohort of early school aged children.Scientific reports · 2024Article
- Maternal risk factors for fetal alcohol spectrum disorders: Distal variables.Alcohol, clinical & experimental research · 2024Article
- Maternal and paternal risk factors for fetal alcohol spectrum disorders: Alcohol and other drug use as proximal influences.Alcohol, clinical & experimental research · 2023Article
- Significance of Selected Environmental and Biological Factors on the Risk of FASD in Women Who Drink Alcohol during Pregnancy.Journal of clinical medicine · 2023Article
- Understanding the Mechanisms of Action and Effects of Drugs of Abuse.Molecules (Basel, Switzerland) · 2023Review
- Dietary Perspectives and Practices during Pregnancy in Rural Amhara Region of Ethiopia: An Exploratory Qualitative Study.Current developments in nutrition · 2023Article
- Reducing Prenatal Alcohol Exposure and the Incidence of FASD: Is the Past Prologue?Alcohol research : current reviews · 2023Review
- DNA methylation as a potential mediator of the association between prenatal tobacco and alcohol exposure and child neurodevelopment in a South African birth cohort.Translational psychiatry · 2022Article
- Pharmacological activation of the Sonic hedgehog pathway with a Smoothened small molecule agonist ameliorates the severity of alcohol-induced morphological and behavioral birth defects in a zebrafish model of fetal alcohol spectrum disorder.Journal of neuroscience research · 2022Article
- Oligodendrocyte lineage is severely affected in human alcohol-exposed foetuses.Acta neuropathologica communications · 2022Article
- Nutritionists' Practices and Knowledge about the Risks of Alcohol Consumption during Pregnancy: An Israeli Survey.Nutrients · 2022Article
- A data driven approach to identify trajectories of prenatal alcohol consumption in an Australian population-based cohort of pregnant women.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesFetal alcohol spectrum disorders (FASD) is a worldwide problem. Maternal alcohol consumption is an important risk factor for FASD. It remains unknown which alcohol consumption patterns most strongly predict FASD. The objective of this study was to identify these.
designSystematic literature review.
methodsWe searched in PubMed, PsychINFO, PsycARTICLES, ERIC, CINAHL, Embase and MEDLINE up to August 2018. The query consisted of keywords and their synonyms related to FASD, pregnancy and behaviour. Studies were excluded when not published in English, were reviews or involved non-human subjects. Substantial heterogeneity precluded aggregation or meta-analysis of the data. Instead, data were qualitatively inspected.
resultsIn total, 21 studies were eligible for further data analysis. All studies that measured both maternal alcohol drinking behaviours and FASD reported retrospective data on maternal drinking patterns, employing both continuous and categorical measures and exhibiting substantial heterogeneity in measures of alcohol consumption (eg, timing of exposure, quantification of alcohol measure and definition of a standard drink). Study quality improved over time and appeared higher for studies based on active case ascertainment, especially when conducted in schools and when behaviour was assessed through interviews.
conclusionsWe aimed to identify specific maternal drinking behaviour(s) related to FASD. The state of the literature precludes such conclusions. Evidence-based preventive measures necessitate identifying which prenatal alcohol drinking behaviour(s) are most in need of intervention. Therefore, we formulate three recommendations for future research. First, future studies can optimise the value of the collected dataset through specifying measurements and reporting of maternal drinking behaviours and avoiding categorised measures (nominal or ordinal) whenever possible. Second, samples should not be selected based on FASD status, but instead, FASD status as well as maternal alcohol consumption should both be measured in a general population sample. Finally, we provide 10 reporting guidelines for FASD research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.