Evidence map›Paper›PMID 30573422›Full record

ReviewThe journal of allergy and clinical immunology. In practice2019

Controversies in Drug Allergy: Drug Allergy Pathways.

Anca M Chiriac, Aleena Banerji, Rebecca S Gruchalla, Bernard Y H Thong, Paige Wickner, Paul-Michel Mertes, Ingrid Terreehorst, Kimberly G Blumenthal

Abstract readReview
In one paragraph

Review in The journal of allergy and clinical immunology. In practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. A new pathway for penicillin delabeling in Norway.The World Allergy Organization journal · 2023
    Article
  5. Delabeling, safety, and impact of β-lactam allergy testing: A systematic review.The journal of allergy and clinical immunology. Global · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Outcome of a de-labelling algorithm compared with results of penicillin (β-lactam) allergy testing.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Penicillin Allergy Testing Is Cost-Saving: An Economic Evaluation Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  14. Allergy to penicillin and betalactam antibiotics.Einstein (Sao Paulo, Brazil) · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Anca M ChiriacDepartment of Pulmonology, Division of Allergy, Hôpital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France; UPMC Univ Paris 06, UMRS 1136; Equipe-EPAR-IPLESP, Sorbonne Universités, Paris, France.
Aleena BanerjiDivision of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass.
Rebecca S GruchallaDivision of Allergy and Immunology, University of Texas Southwestern Medical Center, Dallas, Tex.
Bernard Y H ThongDepartment of Rheumatology, Allergy & Immunology, Tan Tock Seng Hospital, Novena, Singapore.
Paige WicknerDepartment of Medicine, Harvard Medical School, Boston, Mass; Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Mass.
Paul-Michel MertesDepartment of Anesthesia and Intensive Care, University Hospital of Strasbourg, Nouvel Hopital Civil, Strasbourg, France.
Ingrid TerreehorstDepartment of ENT, Amsterdam Medical Centre, Amsterdam, the Netherlands.
Kimberly G BlumenthalDivision of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass. Electronic address: kblumenthal@mgh.harvard.edu.

Funding

The Clinical and Economic Impact of Penicillin AllergyK01AI125631 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BLUMENTHAL, KIMBERLY GOLD · 2016 to 2021
$779k
NIAID NIH HHS K01 AI125631
6 · The paper itself

Abstract

Drug allergy pathways are standardized approaches for patients reporting prior drug allergies with the aim of quality improvement and promotion of antibiotic stewardship. At the International Drug Allergy Symposium during the 2018 American Academy of Allergy, Asthma, and Immunology/World Allergy Organization Joint Congress in Orlando, Florida, drug allergy pathways were discussed from international perspectives with a focus on beta-lactam allergy pathways and pragmatic approaches for acute care hospitals. In this expert consensus document, we review current pathways, and detail important considerations in devising, implementing, and evaluating beta-lactam allergy pathways for hospitalized patients. We describe the key patient and institutional factors that must be considered in risk stratification, the central feature of pathway design. We detail shared obstacles to widespread beta-lactam allergy pathway implementation and identify potential solutions to address these challenges.

Indexed as

ConsensusAllergensAnti-Bacterial Agentsbeta-LactamsCongresses as TopicDrug HypersensitivityDrug-Related Side Effects and Adverse ReactionsExpert TestimonyHumansInternational CooperationPolicyPractice Guidelines as TopicQuality ImprovementRisk AdjustmentUnited StatesAllergensAnti-Bacterial Agentsbeta-LactamsAdverse drug reactionAllergyBeta-lactamDrugGraded challengeGuidelineHypersensitivityPenicillinPolicyQuality improvementSkin testStewardshipTest dose

Identifiers

PMID30573422
PMCPMC6466632

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.