Evidence map›Paper›PMID 30573330›Full record

ArticleJournal of infection and public health

The epidemiology and severity of respiratory viral infections in a tropical country: Ecuador, 2009-2016.

Saverio Caini, Doménica de Mora, Maritza Olmedo, Denisses Portugal, María A Becerra, Marcela Mejía, María C Pacurucu, Jenny Ojeda, Guglielmo Bonaccorsi, Chiara Lorini and 2 more

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In one paragraph

Article in Journal of infection and public health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  20. Comparison of clinical characteristics and outcomes between respiratory syncytial virus and influenza-related pneumonia in China from 2013 to 2019.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saverio CainiNetherlands Institute for Health Services Research (NIVEL), Utrecht, The Netherlands. Electronic address: s.caini@nivel.nl.
Doménica de MoraNational Institute of Public Health Research (INSPI), Guayaquil, Ecuador.
Maritza OlmedoNational Institute of Public Health Research (INSPI), Guayaquil, Ecuador.
Denisses PortugalNational Institute of Public Health Research (INSPI), Guayaquil, Ecuador.
María A BecerraNational Institute of Public Health Research (INSPI), Quito, Ecuador.
Marcela MejíaNational Institute of Public Health Research (INSPI), Cuenca, Ecuador.
María C PacurucuNational Institute of Public Health Research (INSPI), Cuenca, Ecuador.
Jenny OjedaMinistry of Public Health, Guayaquil, Ecuador.
Guglielmo BonaccorsiUniversità degli Studi di Firenze, Florence, Italy.
Chiara LoriniUniversità degli Studi di Firenze, Florence, Italy.
John PagetNetherlands Institute for Health Services Research (NIVEL), Utrecht, The Netherlands.
Alfredo BrunoNational Institute of Public Health Research (INSPI), Guayaquil, Ecuador; Universidad Agraria del Ecuador, Guayaquil, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory viral infections (RVI) are a leading cause of mortality worldwide. We compared the epidemiology and severity of RVI in Ecuador during 2009-2016.

methodsRespiratory specimens collected within the national surveillance system were tested for influenza viruses, respiratory syncytial virus (RSV), adenovirus, parainfluenza virus, and human metapneumovirus. Overall and virus-specific positive detection rate (PDR) were calculated and compared the timing of epidemics caused by the different viruses. Logistic regression models were used to compare the age distribution and risk of death across respiratory viruses.

resultsA total of 41,172 specimens were analyzed: influenza (PDR=14.3%) and respiratory syncytial virus (RSV) (PDR=9.5%) were the most frequently detected viruses. Influenza epidemics typically peaked in December-January and RSV epidemics in March; seasonality was less evident for the other viruses. Compared to adults, children were more frequently infected with RSV, adenovirus, parainfluenza, and influenza B, while the elderly were less frequently infected with influenza A(H1N1)p. The age-adjusted risk of death was highest for A(H1N1)p (odds ratio [OR] 1.73, 95% confidence intervals [CI] 1.38-2.17), and lowest for RSV (OR 0.75, 95%CI 0.57-0.98).

conclusionsWhilst influenza and RSV were the most frequently detected pathogens, the risk of death differed by RVI, being highest for pandemic influenza and lowest for RSV.

Indexed as

AdolescentAdultAgedAge FactorsChildChild, PreschoolEcuadorFemaleHumansInfantInfant, NewbornInfluenza A Virus, H1N1 SubtypeMaleMetapneumovirusMiddle AgedPopulation SurveillanceAge distributionCase-fatality ratioEcuadorEpidemiologyRespiratory viral infections

Identifiers

PMID30573330
PMCPMC7102740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.