Evidence map›Paper›PMID 30573185›Full record

ReviewSeminars in radiation oncology2019

Targeting NAD

Joshua E Lewis, Naveen Singh, Reetta J Holmila, Baran D Sumer, Noelle S Williams, Cristina M Furdui, Melissa L Kemp, David A Boothman

Abstract readReview
In one paragraph

Review in Seminars in radiation oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Redox organization of living systems.Free radical biology & medicine · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joshua E LewisThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA. Electronic address: joshlewis@gatech.edu.
Naveen SinghDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Reetta J HolmilaDepartment of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
Baran D SumerDepartments of Surgery, UT Southwestern Medical Center, Dallas, TX.
Noelle S WilliamsDepartments of Biochemistry, UT Southwestern Medical Center, Dallas, TX.
Cristina M FurduiDepartment of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
Melissa L KempThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA.
David A BoothmanDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Use of Beta-Lapachone for Lung Cancer ChemotherapyR01CA102792 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI BOOTHMAN, DAVID A · 2003 to 2017
$5.3M
Model-based Prediction of Redox-Modulated Responses to Cancer TreatmentsU01CA215848 · NCI · GEORGIA INSTITUTE OF TECHNOLOGY · PI FURDUI, CRISTINA MARIA, KEMP, MELISSA LAMBETH · 2017 to 2021
$3.6M
Exploiting IR inducible NQ01 Levels Using Beta LapachoneR01CA092250 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI BOOTHMAN, DAVID A · 2001 to 2003
$741k
NCI NIH HHS R01 CA092250NCI NIH HHS R01 CA102792NCI NIH HHS U01 CA215848NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

Nicotinamide adenine dinucleotide (NAD

Indexed as

HumansNADNeoplasmsRadiation, IonizingRadiation-Sensitizing AgentsRadiation ToleranceSignal TransductionNADRadiation-Sensitizing Agents

Identifiers

PMID30573185
PMCPMC6310039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.