Evidence map›Paper›PMID 30572960›Full record

ArticleVeterinary research2018

Low levels of classical BSE infectivity in rendered fat tissue.

Christine Fast, Markus Keller, Martin Kaatz, Ute Ziegler, Martin H Groschup

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christine FastInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institute, Südufer 10, 17493, Greifswald-Isle of Riems, Germany.
Markus KellerInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institute, Südufer 10, 17493, Greifswald-Isle of Riems, Germany.
Martin KaatzInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institute, Südufer 10, 17493, Greifswald-Isle of Riems, Germany.
Ute ZieglerInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institute, Südufer 10, 17493, Greifswald-Isle of Riems, Germany.
Martin H GroschupInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institute, Südufer 10, 17493, Greifswald-Isle of Riems, Germany. Martin.Groschup@fli.de.ORCID http://orcid.org/0000-0003-0215-185X
Friedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BSE infectivity in mesentery fat is most likely associated with embedded nervous tissue. To prove this mesentery containing celiac ganglion was taken from oral BSE infected cattle in different stages of the disease and from one control animal. Fat was rendered according to standard tallow production methods and the prion infectivity therein analysed in transgenic mouse bioassay. Rendered fat of the clinical animal revealed low infectivity levels, whereas preclinical and control animals remained negative. This study, although not representative, provides a proof of principle, indicating the potential contamination of melted mesenteric fat by embedded nervous structures during standard tallow production.

Indexed as

Abdominal FatAnimalsCattleEncephalopathy, Bovine SpongiformGanglia, SympatheticMesenteryMiceMice, Transgenic

Identifiers

PMID30572960
PMCPMC6302288
OpenAlexW2905226115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.