ArticleBMC pediatrics2018
Antibiotic prescribing in paediatric inpatients in Ghana: a multi-centre point prevalence survey.
Article in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 5 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- National and regional challenges of antibiotic prescribing patterns in pediatric populations across Africa: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- Improving antibiotic utilization in West Africa: enhancing interventions through systematic review and evidence synthesis.Antimicrobial resistance and infection control · 2025Pooled it
- Surveillance of antimicrobial utilization in Africa: a systematic review and meta-analysis of prescription rates, indications, and quality of use from point prevalence surveys.Antimicrobial resistance and infection control · 2024Pooled it
- Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Antibiotic Use Among Hospitalized Patients in Africa: A Systematic Review of Point Prevalence Studies.Journal of racial and ethnic health disparities · 2024Pooled it
- Antimicrobial Prescribing during Infant Hospital Admissions in a Birth Cohort in Dhaka, Bangladesh.Journal of tropical pediatrics · 2021Trial
- Antibiotic dispensing practices and patterns of non-prescription antibiotic sales among retail drug outlets in Ghana.BMC public health · 2026Article
- Acute Respiratory Infections in Ghanaian Children: Epidemiology, Antimicrobial Resistance, and Prevention Strategies.Pathogens (Basel, Switzerland) · 2026Review
- Standardizing Antimicrobial Use in a Resource-Limited Pediatric Surgical Unit in Botswana.Open forum infectious diseases · 2026Article
- Antibiotic Use in Pediatric Care in Ghana: A Call to Action for Stewardship in This Population.Antibiotics (Basel, Switzerland) · 2025Article
- Appropriateness of Antibiotic Prescription Among Children Under 5 Years: A Cross-Sectional Study in a Ghanaian Regional Hospital.Health science reports · 2025Article
- Analysis of the practice of switch of antibiotics from intravenous to oral therapy at a tertiary care hospital in Nepal: a prospective observational study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- High prevalence of multidrug-resistant and ESBL-producing bacteria in a primary healthcare facility in Accra, Ghana: A cross-sectional study.PLOS global public health · 2025Article
- Age-stratified pharmacovigilance of azithromycin: a multimethod signal detection analysis in the FAERS database.Journal of pharmaceutical policy and practice · 2025Article
- Antibiotic prescribing practices according to the AWaRe classification among children under 5 of age attending public primary care centres in four West African countries: a cross-sectional study (AIRE project, 2021-2022).BMJ paediatrics open · 2024Article
- Antibiotic prescribing patterns in pediatric patients using the WHO access, watch, reserve (AWaRe) classification at a quaternary hospital in Nampula, Mozambique.Scientific reports · 2024Article
- Article
- Healthcare provider cost of antimicrobial resistance in two teaching hospitals in Ghana.Health policy and planning · 2024Article
- Factors influencing C-reactive protein status on admission in neonates after birth.BMC pediatrics · 2024Article
- Article
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Authors and funding
11 authors.
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Abstract
backgroundExcessive and inappropriate use of antibiotics in hospitalised patients contributes to the development and spread of antibiotic resistance. Implementing a stewardship programme to curb the problem requires information on antibiotic use. This study describes a multicentre point prevalence of antibiotic use among paediatric inpatients in Ghana.
methodsData were extracted from a multicentre point prevalence survey of hospital acquired infections in Ghana. Data were collected between September 2016 and December 2016 from ten hospitals through inpatient folder and chart reviews using European Centre for Disease Control (ECDC) adapted data collection instrument. From each site, data were collected within a 12-h period (8 am to 8 pm) by a primary team of research investigators and a select group of health professionals from each participating hospital.
resultsAmong 716 paediatric inpatients, 506 (70.6%; 95% confidence interval (CI): 67.2 to 74.0%) were on antibiotics. A significant proportion of antibiotics (82.9%) was prescribed for infants compared to neonates (63.9%) and adolescents (60.0%). The majority of patients (n = 251, 49.6%) were prescribed two antibiotics at the time of the survey. The top five classes of antibiotics prescribed were third generation cephalosporins (n = 154, 18.5%) aminoglycosides (n = 149, 17.9%), second generation cephalosporins (n = 103,12.4%), beta lactam resistant penicillins (n = 83, 10.0%) and nitroimidazoles (n = 82, 9.9%). The majority of antibiotics (n = 508, 61.0%) were prescribed for community acquired infections. The top three agents for managing community acquired infections were ceftriaxone (n = 97, 19.1%), gentamicin (n = 85, 16.7%) and cefuroxime (n = 73, 14.4%).
conclusionThis study points to high use of antibiotics among paediatric inpatients in Ghana. Cephalosporin use may offer an important target for reduction through antibiotic stewardship programmes.
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