Evidence map›Paper›PMID 30572662›Full record

ArticleCancers2018

Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease.

Annkathrin Hanssen, Carlotta Riebensahm, Malte Mohme, Simon A Joosse, Janna-Lisa Velthaus, Lars Arne Berger, Christian Bernreuther, Markus Glatzel, Sonja Loges, Katrin Lamszus and 4 more

Abstract read
In one paragraph

Article in Cancers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

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  19. Tumour invasion and dissemination.Biochemical Society transactions · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Annkathrin HanssenDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. annkathrin.hanssen@yahoo.de.
Carlotta RiebensahmDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. carlotta.riebensahm@insel.ch.
Malte MohmeDepartment of Neurosurgery University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. m.mohme@uke.de.
Simon A JoosseDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. s.joosse@uke.de.ORCID 0000-0002-4296-5615
Janna-Lisa VelthausDepartment of Internal Medicine II and Clinic (Oncology Centre) University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. j.velthaus@uke.de.
Lars Arne BergerDepartment of Internal Medicine II and Clinic (Oncology Centre) University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. l.berger@uke.de.ORCID 0000-0003-3382-6506
Christian BernreutherInstitute of Neuropathology University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. c.bernreuther@uke.de.
Markus GlatzelInstitute of Neuropathology University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. m.glatzel@uke.de.
Sonja LogesDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. s.loges@uke.de.
Katrin LamszusDepartment of Neurosurgery University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. lamszus@uke.uni-hamburg.de.
Manfred WestphalDepartment of Neurosurgery University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. westphal@uke.de.
Sabine RiethdorfDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. s.riethdorf@uke.de.
Klaus PantelDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. pantel@uke.de.
Harriet WikmanDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany. h.wikman@uke.de.ORCID 0000-0001-6862-0888

Funding

Seventh Framework Programme n° 115749
6 · The paper itself

Abstract

Forty percent of non-small cell lung cancer (NSCLC) patients develop brain metastases, resulting in a dismal prognosis. However, patients in an oligo-metastatic brain disease setting seem to have better outcomes. Here, we investigate the possibility of using circulating tumor cells (CTCs) as biomarkers to differentiate oligo-metastatic patients for better risk assessment. Using the CellSearch

Indexed as

brain metastasiscirculating tumor cell (CTC)EpCAMlung canceroligo-metastasissurvival

Identifiers

PMID30572662
PMCPMC6315958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.